Class 12 Exam  >  Class 12 Videos  >  L16 : Amino acid linkage, peptide bond - Biomolecules, Chemistry, Class 12

L16 : Amino acid linkage, peptide bond - Biomolecules, Chemistry, Class 12 Video Lecture

FAQs on L16 : Amino acid linkage, peptide bond - Biomolecules, Chemistry, Class 12 Video Lecture

1. What is an amino acid linkage and how is it formed?
Ans. An amino acid linkage, also known as a peptide bond, is a chemical bond that forms between two amino acids during protein synthesis. It occurs through a condensation reaction, where the carboxyl group of one amino acid reacts with the amino group of another amino acid, resulting in the release of a water molecule. This linkage is important for the formation of polypeptide chains in proteins.
2. How does the peptide bond contribute to the structure and function of proteins?
Ans. The peptide bond plays a crucial role in determining the structure and function of proteins. It forms the backbone of the protein chain, as it connects individual amino acids in a linear fashion. This linear arrangement allows proteins to fold into specific three-dimensional shapes, which are essential for their function. Additionally, the peptide bond's double bond character restricts rotation around the bond, which influences the protein's stability and conformation.
3. What are the characteristics of a peptide bond?
Ans. Peptide bonds have several distinct characteristics. Firstly, they are formed between the carboxyl group (-COOH) of one amino acid and the amino group (-NH2) of another amino acid. Secondly, they are covalent bonds, meaning they involve the sharing of electrons between atoms. Thirdly, peptide bonds have partial double bond character, resulting from resonance within the peptide group. Lastly, they are relatively stable under physiological conditions, allowing proteins to maintain their structure and function.
4. Can peptide bonds be broken? If yes, how?
Ans. Yes, peptide bonds can be broken through a process called hydrolysis. Hydrolysis of a peptide bond involves the addition of a water molecule, which results in the separation of the two amino acids. This reaction is catalyzed by enzymes called proteases, which are responsible for breaking down proteins into their constituent amino acids. Hydrolysis can occur under acidic, basic, or enzymatic conditions, leading to the degradation of proteins.
5. How is the peptide bond different from other types of chemical bonds?
Ans. The peptide bond differs from other types of chemical bonds in several ways. Firstly, it is a specific type of covalent bond that forms between amino acids exclusively. In contrast, other covalent bonds can occur between a variety of elements and compounds. Secondly, the peptide bond has partial double bond character, resulting in restricted rotation around the bond. This characteristic is not observed in most other covalent bonds. Lastly, the peptide bond is crucial for the formation of proteins, while other types of bonds may serve different functions in various molecules.
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