False.

Anti-symmetrically loaded structures refer to structures that are subjected to loads that are symmetrically distributed about a vertical plane, but with opposite magnitudes. On the other hand, non-symmetrically loaded structures are subjected to loads that do not possess any symmetry.

Indeterminate analysis is a method used to determine the internal forces and deformations in a structure when there are more unknowns than available equilibrium equations. It is commonly used for analyzing complex structures that cannot be easily solved using basic equilibrium equations.

Indeterminate analysis of anti-symmetrically loaded structures can indeed be more difficult compared to non-symmetric ones due to the following reasons:

1. Additional unknowns: Anti-symmetric loading creates additional unknowns in the analysis. The presence of opposite magnitudes of loads on either side of the vertical plane introduces internal forces and deformations that need to be determined.

2. Complexity in equilibrium equations: The presence of additional unknowns results in a more complex set of equilibrium equations. Solving these equations requires a higher level of mathematical analysis, such as using methods like the method of sections, virtual work, or the moment distribution method.

3. Increased complexity in structural behavior: Anti-symmetric loading can lead to more complex structural behavior. The distribution of internal forces and deformations may not follow simple patterns, and the structural response may be affected by factors such as material properties, boundary conditions, and geometric constraints.

4. Increased sensitivity to small changes: Anti-symmetrically loaded structures can be more sensitive to small changes in the loading or boundary conditions. This sensitivity arises from the interaction between the opposite magnitudes of loads, which can amplify the effects of small variations.

Overall, while indeterminate analysis can be challenging for both anti-symmetrically loaded and non-symmetrically loaded structures, the presence of additional unknowns and increased complexity in equilibrium equations make the analysis of anti-symmetrically loaded structures more difficult.