How many ATP are generated from complete oxidation of one molecule of ...
The number of ATP produced from one molecule of fatty acid depends upon the number of carbon atoms present in the fatty acids.
Palmitate is a 16 carbon fatty acid. One molecule of palmitate gives 8 molecules of acetyl CoA and 8 molecules of acetyl CoA are produced from 7 β -oxidation cycles. In each β -oxidation cycle, one molecule
each of NADH and FADH is produced. Therefore 4 ATP are produced per β -oxidation cycle as 1 NADH gives 2.5 ATP and 1 FADH gives 1.5 ATP.
One molecule of acetyl CoA produces 10 ATP per TCA cycle. Therefore 8 molecules of acetyl CoA will produces = 10 x 8 = 80 ATP.
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How many ATP are generated from complete oxidation of one molecule of ...
The complete oxidation of one molecule of palmitic acid involves several steps, including beta-oxidation and the citric acid cycle (also known as the Krebs cycle). These processes generate ATP through oxidative phosphorylation.
1. Beta-oxidation:
- Palmitic acid is a saturated fatty acid with 16 carbon atoms. It undergoes a series of reactions known as beta-oxidation to generate acetyl-CoA molecules.
- Each round of beta-oxidation removes two carbon units, producing one molecule of acetyl-CoA, one molecule of NADH, and one molecule of FADH2.
- Since palmitic acid has 16 carbon atoms, it goes through 7 rounds of beta-oxidation, resulting in the production of 8 molecules of acetyl-CoA, 7 molecules of NADH, and 7 molecules of FADH2.
2. Citric acid cycle:
- Each molecule of acetyl-CoA enters the citric acid cycle, where it is completely oxidized.
- In the citric acid cycle, each acetyl-CoA molecule generates three molecules of NADH, one molecule of FADH2, and one molecule of GTP (which can be converted to ATP).
3. ATP production:
- Each molecule of NADH generated in both beta-oxidation and the citric acid cycle can produce 2.5 ATP through oxidative phosphorylation.
- Each molecule of FADH2 generated in both beta-oxidation and the citric acid cycle can produce 1.5 ATP through oxidative phosphorylation.
- Each molecule of GTP can be converted to ATP, resulting in the production of one ATP.
Calculating the total ATP production:
- 7 molecules of NADH from beta-oxidation = 7 x 2.5 ATP = 17.5 ATP
- 7 molecules of FADH2 from beta-oxidation = 7 x 1.5 ATP = 10.5 ATP
- 8 molecules of NADH from the citric acid cycle = 8 x 2.5 ATP = 20 ATP
- 8 molecules of FADH2 from the citric acid cycle = 8 x 1.5 ATP = 12 ATP
- 8 molecules of GTP from the citric acid cycle = 8 ATP
Total ATP production = 17.5 + 10.5 + 20 + 12 + 8 = 68 ATP
Therefore, the correct answer is option 'D' - 68 ATP.