IIT JAM Exam > IIT JAM Questions > Which one of the following statements about c...
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Which one of the following statements about cytochromes P450 is/are CORRECT?
- a)They are able to accept electrons from either NADH or NADPH.
- b)They are found only in the endoplasmic reticulum.
- c)They are monooxygenase enzymes.
- d)They play a major role in drug detoxification in the liver.
Correct answer is option 'C,D'. Can you explain this answer?
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Which one of the following statements about cytochromes P450 is/are CO...
Option (b) is incorrect as cytochromes p450 are located mainly in the endoplasmic reticulum but they are also found in mitochondria in some tissues. Cytochrome P450 enzymes also function to metabolize potentially toxic compounds, including drugs and products of endogenous metabolism such as bilirubin, principally in the liver. The Human Genome Project has identified 57 human genes coding for the various cytochrome P450 enzymes.
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Which one of the following statements about cytochromes P450 is/are CO...
Cytochromes P450 are a group of heme-containing enzymes that play a crucial role in the metabolism of various endogenous and exogenous compounds. Here are the correct statements regarding cytochromes P450:
C) They are monooxygenase enzymes
Cytochromes P450 are monooxygenase enzymes as they catalyze the introduction of a single oxygen atom from molecular oxygen into a substrate molecule.
D) They play a major role in drug detoxification in the liver
Cytochromes P450 play a major role in drug detoxification in the liver by metabolizing various xenobiotics, including drugs, environmental pollutants, and carcinogens. The enzymes convert lipophilic compounds into more polar metabolites that can be excreted from the body.
A) They are able to accept electrons from either NADH or NADPH
Cytochromes P450 can accept electrons from both NADH and NADPH, which are co-factors that provide reducing power for the enzyme to carry out its monooxygenase activity.
B) They are found only in the endoplasmic reticulum
This statement is incorrect. Although cytochromes P450 are predominantly found in the endoplasmic reticulum of liver cells, they are also present in other cell types and organelles, such as the mitochondria.
In summary, cytochromes P450 are monooxygenase enzymes that play a major role in drug detoxification in the liver. They can accept electrons from either NADH or NADPH and are found in various cell types and organelles.
C) They are monooxygenase enzymes
Cytochromes P450 are monooxygenase enzymes as they catalyze the introduction of a single oxygen atom from molecular oxygen into a substrate molecule.
D) They play a major role in drug detoxification in the liver
Cytochromes P450 play a major role in drug detoxification in the liver by metabolizing various xenobiotics, including drugs, environmental pollutants, and carcinogens. The enzymes convert lipophilic compounds into more polar metabolites that can be excreted from the body.
A) They are able to accept electrons from either NADH or NADPH
Cytochromes P450 can accept electrons from both NADH and NADPH, which are co-factors that provide reducing power for the enzyme to carry out its monooxygenase activity.
B) They are found only in the endoplasmic reticulum
This statement is incorrect. Although cytochromes P450 are predominantly found in the endoplasmic reticulum of liver cells, they are also present in other cell types and organelles, such as the mitochondria.
In summary, cytochromes P450 are monooxygenase enzymes that play a major role in drug detoxification in the liver. They can accept electrons from either NADH or NADPH and are found in various cell types and organelles.
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Which one of the following statements about cytochromes P450 is/are CORRECT?a)They are able to accept electrons from either NADH or NADPH.b)They are found only in the endoplasmic reticulum.c)They are monooxygenase enzymes.d)They play a major role in drug detoxification in the liver.Correct answer is option 'C,D'. Can you explain this answer?
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Which one of the following statements about cytochromes P450 is/are CORRECT?a)They are able to accept electrons from either NADH or NADPH.b)They are found only in the endoplasmic reticulum.c)They are monooxygenase enzymes.d)They play a major role in drug detoxification in the liver.Correct answer is option 'C,D'. Can you explain this answer? for IIT JAM 2024 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about Which one of the following statements about cytochromes P450 is/are CORRECT?a)They are able to accept electrons from either NADH or NADPH.b)They are found only in the endoplasmic reticulum.c)They are monooxygenase enzymes.d)They play a major role in drug detoxification in the liver.Correct answer is option 'C,D'. Can you explain this answer? covers all topics & solutions for IIT JAM 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Which one of the following statements about cytochromes P450 is/are CORRECT?a)They are able to accept electrons from either NADH or NADPH.b)They are found only in the endoplasmic reticulum.c)They are monooxygenase enzymes.d)They play a major role in drug detoxification in the liver.Correct answer is option 'C,D'. Can you explain this answer?.
Which one of the following statements about cytochromes P450 is/are CORRECT?a)They are able to accept electrons from either NADH or NADPH.b)They are found only in the endoplasmic reticulum.c)They are monooxygenase enzymes.d)They play a major role in drug detoxification in the liver.Correct answer is option 'C,D'. Can you explain this answer? for IIT JAM 2024 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about Which one of the following statements about cytochromes P450 is/are CORRECT?a)They are able to accept electrons from either NADH or NADPH.b)They are found only in the endoplasmic reticulum.c)They are monooxygenase enzymes.d)They play a major role in drug detoxification in the liver.Correct answer is option 'C,D'. Can you explain this answer? covers all topics & solutions for IIT JAM 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Which one of the following statements about cytochromes P450 is/are CORRECT?a)They are able to accept electrons from either NADH or NADPH.b)They are found only in the endoplasmic reticulum.c)They are monooxygenase enzymes.d)They play a major role in drug detoxification in the liver.Correct answer is option 'C,D'. Can you explain this answer?.
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Which one of the following statements about cytochromes P450 is/are CORRECT?a)They are able to accept electrons from either NADH or NADPH.b)They are found only in the endoplasmic reticulum.c)They are monooxygenase enzymes.d)They play a major role in drug detoxification in the liver.Correct answer is option 'C,D'. Can you explain this answer?, a detailed solution for Which one of the following statements about cytochromes P450 is/are CORRECT?a)They are able to accept electrons from either NADH or NADPH.b)They are found only in the endoplasmic reticulum.c)They are monooxygenase enzymes.d)They play a major role in drug detoxification in the liver.Correct answer is option 'C,D'. Can you explain this answer? has been provided alongside types of Which one of the following statements about cytochromes P450 is/are CORRECT?a)They are able to accept electrons from either NADH or NADPH.b)They are found only in the endoplasmic reticulum.c)They are monooxygenase enzymes.d)They play a major role in drug detoxification in the liver.Correct answer is option 'C,D'. Can you explain this answer? theory, EduRev gives you an
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