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The presence of D-amino acids in the cross links of peptidoglycan layer is most likely because
  • a)
    D-amino acids fit the structural constrains of the cell wall better than L-amino acids.
  • b)
    Most L-amino acids have already been used for protein synthesis.
  • c)
    D-amino acids are easier to cross link in the absence of ribosomes.
  • d)
    Most peptidases can only cleave L-amino acids.
Correct answer is option 'D'. Can you explain this answer?
Verified Answer
The presence of D-amino acids in the cross links of peptidoglycan laye...
D-amino acids are most likely present in cross links of peptidioglycan layer as proteases easily cleave L-amino acids.
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The presence of D-amino acids in the cross links of peptidoglycan laye...
D-amino acids are mirror images of L-amino acids, differing only in the orientation of their functional groups. In the context of the peptidoglycan layer, which is a major component of bacterial cell walls, the presence of D-amino acids in the cross-links is most likely because most peptidases can only cleave L-amino acids.

Explanation:
Peptidoglycan is a complex polymer that provides strength and rigidity to the bacterial cell wall. It consists of alternating units of N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM), which are connected by short peptide chains. These peptide chains are cross-linked to form a 3D network, providing structural integrity to the cell wall.

One of the important steps in the synthesis of peptidoglycan is the cross-linking of the peptide chains. This process involves the formation of covalent bonds between the amino acid residues of adjacent peptide chains. The cross-linking reaction is catalyzed by enzymes called transpeptidases or penicillin-binding proteins (PBPs).

The reason why D-amino acids are present in the cross-links of peptidoglycan is that most peptidases, which are enzymes that break down peptides, can only cleave L-amino acids. By incorporating D-amino acids into the peptide chains, bacteria can protect the peptidoglycan layer from degradation by peptidases, making the cell wall more resistant to attack.

With the presence of D-amino acids in the cross-links, peptidases are unable to recognize and cleave these bonds effectively, thus maintaining the structural integrity of the peptidoglycan layer. This provides a selective advantage to bacteria by preventing the breakdown of their cell walls and enhancing their resistance against external threats.

Therefore, the most likely reason for the presence of D-amino acids in the cross-links of the peptidoglycan layer is to protect the cell wall from degradation by peptidases, as most peptidases can only cleave L-amino acids.
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The presence of D-amino acids in the cross links of peptidoglycan layer is most likely becausea)D-amino acids fit the structural constrains of the cell wall better than L-amino acids.b)Most L-amino acids have already been used for protein synthesis.c)D-amino acids are easier to cross link in the absence of ribosomes.d)Most peptidases can only cleave L-amino acids.Correct answer is option 'D'. Can you explain this answer?
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The presence of D-amino acids in the cross links of peptidoglycan layer is most likely becausea)D-amino acids fit the structural constrains of the cell wall better than L-amino acids.b)Most L-amino acids have already been used for protein synthesis.c)D-amino acids are easier to cross link in the absence of ribosomes.d)Most peptidases can only cleave L-amino acids.Correct answer is option 'D'. Can you explain this answer? for IIT JAM 2024 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about The presence of D-amino acids in the cross links of peptidoglycan layer is most likely becausea)D-amino acids fit the structural constrains of the cell wall better than L-amino acids.b)Most L-amino acids have already been used for protein synthesis.c)D-amino acids are easier to cross link in the absence of ribosomes.d)Most peptidases can only cleave L-amino acids.Correct answer is option 'D'. Can you explain this answer? covers all topics & solutions for IIT JAM 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for The presence of D-amino acids in the cross links of peptidoglycan layer is most likely becausea)D-amino acids fit the structural constrains of the cell wall better than L-amino acids.b)Most L-amino acids have already been used for protein synthesis.c)D-amino acids are easier to cross link in the absence of ribosomes.d)Most peptidases can only cleave L-amino acids.Correct answer is option 'D'. Can you explain this answer?.
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