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Find out the correct statement-
  • a)
    cdc-25 is a phosphatase which helps in formation of active MPF.
  • b)
    Cyclin-E  required for G1 to S transition
  • c)
    In G0 phase cell is not metabolically active
  • d)
    The concentration of cyclin-D is high in G1 phase.
Correct answer is option 'A,B,D'. Can you explain this answer?
Verified Answer
Find out the correct statement-a)cdc-25 is a phosphatase which helps i...
In the G0 phase the cell is metabolically active
cdc-25 is a phosphatase and it is involved in the last step of formation of active MPF. For G1 to S transition cyclin -E is required.
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Find out the correct statement-a)cdc-25 is a phosphatase which helps i...
Explanation of Correct Statements
The correct statements regarding cell cycle regulation and protein interactions are:
1. cdc-25 is a phosphatase which helps in formation of active MPF.
- cdc-25 plays a crucial role in activating the Maturation-Promoting Factor (MPF) by dephosphorylating specific sites on cyclin-dependent kinase (CDK).
- This activation is essential for the cell to progress from G2 phase to M phase (mitosis), thus facilitating cell division.
2. Cyclin-E required for G1 to S transition.
- Cyclin E is critical for the progression from the G1 phase to the S phase of the cell cycle.
- It forms a complex with CDK2, which helps in the initiation of DNA replication, signaling the cell to enter the S phase.
3. In G0 phase cell is not metabolically active.
- The G0 phase is a quiescent state where cells are in a resting phase and do not actively divide.
- However, it is important to note that cells in G0 can still perform basic metabolic functions, though they are not preparing for division.
4. The concentration of cyclin-D is high in G1 phase.
- Cyclin D is indeed prevalent during the G1 phase and is essential for the progression of the cell cycle by activating CDK4 and CDK6.
- This activation allows the cell to move past the restriction point, leading to DNA synthesis.
Conclusion
Among the listed statements, A, B, and D are correct. Statement C, while it describes a phase of the cell cycle, inaccurately portrays the metabolic activity of cells in G0. Cells in G0 can be metabolically active, albeit not in a state of division.
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Find out the correct statement-a)cdc-25 is a phosphatase which helps in formation of active MPF.b)Cyclin-E required for G1to S transitionc)In G0phase cell is not metabolically actived)The concentration of cyclin-D is high in G1phase.Correct answer is option 'A,B,D'. Can you explain this answer? for IIT JAM 2025 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about Find out the correct statement-a)cdc-25 is a phosphatase which helps in formation of active MPF.b)Cyclin-E required for G1to S transitionc)In G0phase cell is not metabolically actived)The concentration of cyclin-D is high in G1phase.Correct answer is option 'A,B,D'. Can you explain this answer? covers all topics & solutions for IIT JAM 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Find out the correct statement-a)cdc-25 is a phosphatase which helps in formation of active MPF.b)Cyclin-E required for G1to S transitionc)In G0phase cell is not metabolically actived)The concentration of cyclin-D is high in G1phase.Correct answer is option 'A,B,D'. Can you explain this answer?.
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