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A young college student had nausea, vomiting, visual disorders, and muscular paralysis after eating canned tuna fish. The probable diagnosis is botulism, caused by ingestion of the Clostridium botulinum toxin. The physiological effect of this toxin is to
- a)inactivate acetylcholinesterase
- b)bind to and thus inactivate acetylcholine receptors at myoneural junctions
- c)prevent release of calcium ions from the sarcoplasmic reticulum, thus inhibiting muscle contraction
- d)inhibit release of acetylcholine from presynaptic membranes
Correct answer is option 'D'. Can you explain this answer?
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A young college student had nausea, vomiting, visual disorders, and mu...
The toxin from Clostridium botulinum inhibits the release of acetylcholine, the neurotransmitter at myoneural junctions. As a result, motor nerve impulses cannot be transmitted across the junction, and muscle cells are not stimulated to contract.
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A young college student had nausea, vomiting, visual disorders, and mu...
Physiological Effect of Clostridium botulinum toxin:
The physiological effect of Clostridium botulinum toxin, which causes botulism, is the inhibition of the release of acetylcholine from presynaptic membranes. Let's understand this in detail:
1. Botulism:
Botulism is a rare but serious illness caused by the ingestion of the Clostridium botulinum toxin. This toxin is produced by the bacterium Clostridium botulinum, which is commonly found in soil and can contaminate certain foods, especially improperly preserved or canned foods.
2. Symptoms:
The symptoms of botulism include nausea, vomiting, visual disorders, and muscular paralysis. These symptoms are consistent with the effect of the Clostridium botulinum toxin on the nervous system.
3. Inhibition of Acetylcholine Release:
The Clostridium botulinum toxin acts by inhibiting the release of acetylcholine from presynaptic membranes. Acetylcholine is a neurotransmitter that plays a crucial role in the transmission of nerve impulses across the neuromuscular junction.
4. Neuromuscular Junction:
The neuromuscular junction is the point of communication between a nerve cell (motor neuron) and a muscle cell. It is responsible for transmitting signals from the nervous system to the muscles, resulting in muscle contraction.
5. Role of Acetylcholine:
Acetylcholine is released from the presynaptic membrane into the synaptic cleft, the small gap between the nerve ending and the muscle fiber. It then binds to acetylcholine receptors located on the postsynaptic membrane of the muscle fiber.
6. Muscle Contraction:
When acetylcholine binds to its receptors at the myoneural junction, it triggers a series of events that ultimately lead to muscle contraction. This involves the release of calcium ions from the sarcoplasmic reticulum, a specialized structure within the muscle fiber.
7. Effect of Clostridium botulinum toxin:
The Clostridium botulinum toxin interferes with the release of acetylcholine from the presynaptic membrane, preventing it from reaching the postsynaptic membrane and binding to its receptors. As a result, the normal transmission of nerve impulses is disrupted, leading to muscle weakness and paralysis.
Conclusion:
In summary, the physiological effect of the Clostridium botulinum toxin is to inhibit the release of acetylcholine from presynaptic membranes. This disrupts the normal transmission of nerve impulses at the neuromuscular junction, resulting in the symptoms of botulism, including muscular paralysis.
The physiological effect of Clostridium botulinum toxin, which causes botulism, is the inhibition of the release of acetylcholine from presynaptic membranes. Let's understand this in detail:
1. Botulism:
Botulism is a rare but serious illness caused by the ingestion of the Clostridium botulinum toxin. This toxin is produced by the bacterium Clostridium botulinum, which is commonly found in soil and can contaminate certain foods, especially improperly preserved or canned foods.
2. Symptoms:
The symptoms of botulism include nausea, vomiting, visual disorders, and muscular paralysis. These symptoms are consistent with the effect of the Clostridium botulinum toxin on the nervous system.
3. Inhibition of Acetylcholine Release:
The Clostridium botulinum toxin acts by inhibiting the release of acetylcholine from presynaptic membranes. Acetylcholine is a neurotransmitter that plays a crucial role in the transmission of nerve impulses across the neuromuscular junction.
4. Neuromuscular Junction:
The neuromuscular junction is the point of communication between a nerve cell (motor neuron) and a muscle cell. It is responsible for transmitting signals from the nervous system to the muscles, resulting in muscle contraction.
5. Role of Acetylcholine:
Acetylcholine is released from the presynaptic membrane into the synaptic cleft, the small gap between the nerve ending and the muscle fiber. It then binds to acetylcholine receptors located on the postsynaptic membrane of the muscle fiber.
6. Muscle Contraction:
When acetylcholine binds to its receptors at the myoneural junction, it triggers a series of events that ultimately lead to muscle contraction. This involves the release of calcium ions from the sarcoplasmic reticulum, a specialized structure within the muscle fiber.
7. Effect of Clostridium botulinum toxin:
The Clostridium botulinum toxin interferes with the release of acetylcholine from the presynaptic membrane, preventing it from reaching the postsynaptic membrane and binding to its receptors. As a result, the normal transmission of nerve impulses is disrupted, leading to muscle weakness and paralysis.
Conclusion:
In summary, the physiological effect of the Clostridium botulinum toxin is to inhibit the release of acetylcholine from presynaptic membranes. This disrupts the normal transmission of nerve impulses at the neuromuscular junction, resulting in the symptoms of botulism, including muscular paralysis.
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A young college student had nausea, vomiting, visual disorders, and muscular paralysis after eating canned tuna fish. The probable diagnosis is botulism, caused by ingestion of the Clostridium botulinum toxin. The physiological effect of this toxin is toa)inactivate acetylcholinesteraseb)bind to and thus inactivate acetylcholine receptors at myoneural junctionsc)prevent release of calcium ions from the sarcoplasmic reticulum, thus inhibiting muscle contractiond)inhibit release of acetylcholine from presynaptic membranesCorrect answer is option 'D'. Can you explain this answer?
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A young college student had nausea, vomiting, visual disorders, and muscular paralysis after eating canned tuna fish. The probable diagnosis is botulism, caused by ingestion of the Clostridium botulinum toxin. The physiological effect of this toxin is toa)inactivate acetylcholinesteraseb)bind to and thus inactivate acetylcholine receptors at myoneural junctionsc)prevent release of calcium ions from the sarcoplasmic reticulum, thus inhibiting muscle contractiond)inhibit release of acetylcholine from presynaptic membranesCorrect answer is option 'D'. Can you explain this answer? for IIT JAM 2024 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about A young college student had nausea, vomiting, visual disorders, and muscular paralysis after eating canned tuna fish. The probable diagnosis is botulism, caused by ingestion of the Clostridium botulinum toxin. The physiological effect of this toxin is toa)inactivate acetylcholinesteraseb)bind to and thus inactivate acetylcholine receptors at myoneural junctionsc)prevent release of calcium ions from the sarcoplasmic reticulum, thus inhibiting muscle contractiond)inhibit release of acetylcholine from presynaptic membranesCorrect answer is option 'D'. Can you explain this answer? covers all topics & solutions for IIT JAM 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for A young college student had nausea, vomiting, visual disorders, and muscular paralysis after eating canned tuna fish. The probable diagnosis is botulism, caused by ingestion of the Clostridium botulinum toxin. The physiological effect of this toxin is toa)inactivate acetylcholinesteraseb)bind to and thus inactivate acetylcholine receptors at myoneural junctionsc)prevent release of calcium ions from the sarcoplasmic reticulum, thus inhibiting muscle contractiond)inhibit release of acetylcholine from presynaptic membranesCorrect answer is option 'D'. Can you explain this answer?.
A young college student had nausea, vomiting, visual disorders, and muscular paralysis after eating canned tuna fish. The probable diagnosis is botulism, caused by ingestion of the Clostridium botulinum toxin. The physiological effect of this toxin is toa)inactivate acetylcholinesteraseb)bind to and thus inactivate acetylcholine receptors at myoneural junctionsc)prevent release of calcium ions from the sarcoplasmic reticulum, thus inhibiting muscle contractiond)inhibit release of acetylcholine from presynaptic membranesCorrect answer is option 'D'. Can you explain this answer? for IIT JAM 2024 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about A young college student had nausea, vomiting, visual disorders, and muscular paralysis after eating canned tuna fish. The probable diagnosis is botulism, caused by ingestion of the Clostridium botulinum toxin. The physiological effect of this toxin is toa)inactivate acetylcholinesteraseb)bind to and thus inactivate acetylcholine receptors at myoneural junctionsc)prevent release of calcium ions from the sarcoplasmic reticulum, thus inhibiting muscle contractiond)inhibit release of acetylcholine from presynaptic membranesCorrect answer is option 'D'. Can you explain this answer? covers all topics & solutions for IIT JAM 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for A young college student had nausea, vomiting, visual disorders, and muscular paralysis after eating canned tuna fish. The probable diagnosis is botulism, caused by ingestion of the Clostridium botulinum toxin. The physiological effect of this toxin is toa)inactivate acetylcholinesteraseb)bind to and thus inactivate acetylcholine receptors at myoneural junctionsc)prevent release of calcium ions from the sarcoplasmic reticulum, thus inhibiting muscle contractiond)inhibit release of acetylcholine from presynaptic membranesCorrect answer is option 'D'. Can you explain this answer?.
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A young college student had nausea, vomiting, visual disorders, and muscular paralysis after eating canned tuna fish. The probable diagnosis is botulism, caused by ingestion of the Clostridium botulinum toxin. The physiological effect of this toxin is toa)inactivate acetylcholinesteraseb)bind to and thus inactivate acetylcholine receptors at myoneural junctionsc)prevent release of calcium ions from the sarcoplasmic reticulum, thus inhibiting muscle contractiond)inhibit release of acetylcholine from presynaptic membranesCorrect answer is option 'D'. Can you explain this answer?, a detailed solution for A young college student had nausea, vomiting, visual disorders, and muscular paralysis after eating canned tuna fish. The probable diagnosis is botulism, caused by ingestion of the Clostridium botulinum toxin. The physiological effect of this toxin is toa)inactivate acetylcholinesteraseb)bind to and thus inactivate acetylcholine receptors at myoneural junctionsc)prevent release of calcium ions from the sarcoplasmic reticulum, thus inhibiting muscle contractiond)inhibit release of acetylcholine from presynaptic membranesCorrect answer is option 'D'. Can you explain this answer? has been provided alongside types of A young college student had nausea, vomiting, visual disorders, and muscular paralysis after eating canned tuna fish. The probable diagnosis is botulism, caused by ingestion of the Clostridium botulinum toxin. The physiological effect of this toxin is toa)inactivate acetylcholinesteraseb)bind to and thus inactivate acetylcholine receptors at myoneural junctionsc)prevent release of calcium ions from the sarcoplasmic reticulum, thus inhibiting muscle contractiond)inhibit release of acetylcholine from presynaptic membranesCorrect answer is option 'D'. Can you explain this answer? theory, EduRev gives you an
ample number of questions to practice A young college student had nausea, vomiting, visual disorders, and muscular paralysis after eating canned tuna fish. The probable diagnosis is botulism, caused by ingestion of the Clostridium botulinum toxin. The physiological effect of this toxin is toa)inactivate acetylcholinesteraseb)bind to and thus inactivate acetylcholine receptors at myoneural junctionsc)prevent release of calcium ions from the sarcoplasmic reticulum, thus inhibiting muscle contractiond)inhibit release of acetylcholine from presynaptic membranesCorrect answer is option 'D'. Can you explain this answer? tests, examples and also practice IIT JAM tests.
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