Explanation:

Drosophila is a genus of small flies, commonly known as fruit flies. They are widely used in genetics research as model organisms. In Drosophila, the sex of an individual is determined by the presence or absence of the Y chromosome, similar to humans.

- Females have two X chromosomes (XX), while males have one X and one Y chromosome (XY).
- Autosomes are non-sex chromosomes, and in Drosophila, there are four pairs of autosomes.

Based on the given information that the Drosophila has 2X chromosomes and 4 autosomes, we can determine its sex.

Explanation of options:

a) Female: Females in Drosophila have two X chromosomes (XX). This option is incorrect because the given Drosophila has 2X chromosomes, but we don't know the presence or absence of the Y chromosome to confirm the sex.

b) Male: Males in Drosophila have one X and one Y chromosome (XY). Since we know that the Drosophila has 2X chromosomes, it cannot be a female and must be a male. This is the correct answer.

c) Metafemale: Metafemales in Drosophila have three or more X chromosomes (XXX or more). Since the given Drosophila has 2X chromosomes, it cannot be a metafemale.

d) Intersex: Intersex individuals have atypical combinations of male and female characteristics. However, based on the given information, we cannot determine the presence or absence of the Y chromosome, which is necessary to determine if the Drosophila is intersex.

Conclusion:

Based on the given information, the Drosophila with 2X chromosomes and 4 autosomes is most likely a male.