Friedel-Craft’s reaction using MeCl and anhydrous AlCl3 will tak...
Friedel-Craft’s reaction using MeCl and anhydrous AlCl3 will tak...
Explanation:
Friedel-Craft's acylation is a type of electrophilic aromatic substitution reaction in which an acyl group is introduced onto an aromatic ring. In this reaction, anhydrous aluminum chloride (AlCl3) acts as a Lewis acid catalyst, facilitating the formation of the acylium ion, which then reacts with the aromatic compound.
Efficiency of Friedel-Craft's reaction:
The efficiency of the Friedel-Craft's reaction using MeCl (methyl chloride) and anhydrous AlCl3 depends on the reactivity of the aromatic compound. Toluene is more reactive towards Friedel-Craft's acylation compared to benzene, nitrobenzene, or acetophenone due to its higher electron density.
Reason for choosing toluene:
- Toluene has a methyl group which is an activating group, increasing the electron density on the aromatic ring.
- The increased electron density makes toluene more susceptible to electrophilic attack, leading to a more efficient Friedel-Craft's acylation reaction.
- Benzene, nitrobenzene, and acetophenone are less reactive due to the presence of deactivating groups or lack of activating groups.
Therefore, the Friedel-Craft's reaction using MeCl and anhydrous AlCl3 will take place most efficiently with toluene among the given options.