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Which of the following represents Schotten Baumann reaction?
  • a)
    formation of amides from amines and acid chlorides/NaOH
  • b)
    for mation of amines from amides an d LiAlH4
  • c)
    formation of amines from amides and Br2/NaOH
  • d)
    formation of amides from oxime and H2SO4
Correct answer is option 'A'. Can you explain this answer?
Verified Answer
Which of the following represents Schotten Baumann reaction?a)formatio...
Schotten-Baumann Conditions

The use of added base to drive the equilibrium in the formation of amides from amines and acid chlorides.
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Which of the following represents Schotten Baumann reaction?a)formatio...
Schotten Baumann Reaction

The Schotten Baumann reaction is a chemical reaction that is used to form amides from amines and acid chlorides. The reaction involves the use of sodium hydroxide as a base, which serves to neutralize the hydrogen chloride generated during the reaction.

Mechanism

The Schotten Baumann reaction proceeds through the following mechanism:

Step 1: Deprotonation

The amine is deprotonated by the base to generate an amide ion.

Step 2: Nucleophilic attack

The amide ion attacks the acid chloride to form an intermediate.

Step 3: Protonation

The intermediate is then protonated by the acid chloride to form the final amide product.

Overall Reaction

The overall reaction for the Schotten Baumann reaction is:

amine + acid chloride + NaOH → amide + NaCl + H2O

Applications

The Schotten Baumann reaction is widely used in organic chemistry for the synthesis of amides, which are important intermediates in the production of pharmaceuticals, agrochemicals, and other fine chemicals.

Conclusion

In conclusion, the Schotten Baumann reaction is a valuable tool for the synthesis of amides from amines and acid chlorides. The reaction proceeds through a straightforward mechanism and has broad synthetic applications.
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Which of the following represents Schotten Baumann reaction?a)formation of amides from amines and acid chlorides/NaOHb)for mation of amines from amides an d LiAlH4c)formation of amines from amides and Br2/NaOHd)formation of amides from oxime and H2SO4Correct answer is option 'A'. Can you explain this answer?
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Which of the following represents Schotten Baumann reaction?a)formation of amides from amines and acid chlorides/NaOHb)for mation of amines from amides an d LiAlH4c)formation of amines from amides and Br2/NaOHd)formation of amides from oxime and H2SO4Correct answer is option 'A'. Can you explain this answer? for JEE 2024 is part of JEE preparation. The Question and answers have been prepared according to the JEE exam syllabus. Information about Which of the following represents Schotten Baumann reaction?a)formation of amides from amines and acid chlorides/NaOHb)for mation of amines from amides an d LiAlH4c)formation of amines from amides and Br2/NaOHd)formation of amides from oxime and H2SO4Correct answer is option 'A'. Can you explain this answer? covers all topics & solutions for JEE 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Which of the following represents Schotten Baumann reaction?a)formation of amides from amines and acid chlorides/NaOHb)for mation of amines from amides an d LiAlH4c)formation of amines from amides and Br2/NaOHd)formation of amides from oxime and H2SO4Correct answer is option 'A'. Can you explain this answer?.
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