Which of the following is a bactericidal antibiotic?a)Erythromycinb)Of...
Antibiotics can either kill the target microbes (cidal effect) or can prevent it from pathogenic action (static effect). The former are known as bactericidal and the latter is known as bacteriostatic.
Which of the following is a bactericidal antibiotic?a)Erythromycinb)Of...
Introduction:
Antibiotics are drugs that are used to treat bacterial infections. They work by either killing the bacteria (bactericidal) or inhibiting their growth and reproduction (bacteriostatic). It is important to differentiate between bactericidal and bacteriostatic antibiotics as the choice of antibiotic depends on the severity and type of infection.
Bactericidal antibiotics:
Bactericidal antibiotics are drugs that kill bacteria directly. They are often preferred in severe infections, immunocompromised patients, or when the patient's immune system is unable to clear the infection on its own. Some examples of bactericidal antibiotics are:
- Penicillins (e.g. amoxicillin, penicillin G)
- Cephalosporins (e.g. ceftriaxone, cephalexin)
- Aminoglycosides (e.g. gentamicin, tobramycin)
- Fluoroquinolones (e.g. ciprofloxacin, levofloxacin)
- Metronidazole
Ofloxacin as a bactericidal antibiotic:
Ofloxacin is a fluoroquinolone antibiotic that is bactericidal. It works by inhibiting the bacterial enzyme DNA gyrase, which is necessary for the replication and repair of bacterial DNA. This leads to the death of the bacteria.
Ofloxacin is effective against a wide range of Gram-positive and Gram-negative bacteria, including aerobic and anaerobic bacteria. It is commonly used to treat respiratory tract infections, urinary tract infections, skin infections, and gastrointestinal infections.
Conclusion:
In conclusion, ofloxacin is a bactericidal antibiotic that is effective against a wide range of bacteria. It works by inhibiting bacterial DNA gyrase and causing the death of the bacteria. It is commonly used to treat respiratory tract infections, urinary tract infections, skin infections, and gastrointestinal infections.