A broad spectrum antibiotic is:a)Paracetamolb)Ampicillinc)Aspirind)PenicillinCorrect answer is option 'B'. Can you explain this answer?

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Answer

Chloramphenicol is a broad spectrum antibiotic that is derived from the bacterium Streptomyces venezuelae it interferes with mitochondrial protein synthesis and is active against a variety of organisms including salmonelloses not responsive to ampicillin.

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Answer

Pencillium

Answer

Chloramphenicol is a broad spectrum antibiotic that is derived from the bacterium Streptomyces venezuelae it interferes with mitochondrial protein synthesis and is active against a variety of organisms including salmonelloses not responsive to ampicillin.

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Chloramphenicol is broad spectrum antibiotic that stops bacterial growth by stopping the production of proteins.it interferes with mitochondrial protein synthesis and is active against a variety of organisms.

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A broad spectrum antibiotic refers to an antibiotic that is effective against a wide range of bacteria, including both Gram-positive and Gram-negative bacteria. It is able to target and kill a variety of different bacterial species, making it a versatile treatment option for various infections. Among the options given, the correct answer is option 'B', Ampicillin. Now let's delve into the details of why Ampicillin is a broad spectrum antibiotic.

Ampicillin as a Broad Spectrum Antibiotic

1. Mechanism of Action
Ampicillin is a penicillin-type antibiotic that works by inhibiting the cell wall synthesis of bacteria. It interferes with the formation of peptidoglycan, a key component of the bacterial cell wall, leading to weakened cell walls and eventual cell lysis. This mechanism of action is effective against a wide range of bacteria.

2. Spectrum of Activity
Ampicillin exhibits activity against both Gram-positive and Gram-negative bacteria. Gram-positive bacteria have a thick peptidoglycan layer, while Gram-negative bacteria have an additional outer membrane. Ampicillin is able to penetrate both types of bacterial cell walls and exert its antibacterial effects.

3. Bacterial Infections Treated
Due to its broad spectrum of activity, Ampicillin can be used to treat various bacterial infections. It is commonly used for respiratory tract infections, urinary tract infections, skin and soft tissue infections, gastrointestinal infections, and certain sexually transmitted infections. These infections can be caused by a wide range of bacterial pathogens, and Ampicillin's effectiveness against both Gram-positive and Gram-negative bacteria makes it suitable for treatment.

4. Limitations and Resistance
While Ampicillin is effective against many bacteria, it is important to note that not all bacteria are susceptible to its effects. Some bacteria have developed resistance mechanisms, such as producing enzymes called beta-lactamases that can inactivate Ampicillin. Therefore, it is crucial to perform antibiotic susceptibility testing to ensure the appropriate use of Ampicillin.

Overall, Ampicillin is classified as a broad spectrum antibiotic because of its ability to target and kill a wide range of bacteria, including Gram-positive and Gram-negative species. Its mechanism of action, spectrum of activity, and effectiveness against various bacterial infections make it a valuable treatment option in clinical practice.

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