Which of the following statements is not correct regarding IgM antibod...
IgM is the first antibody which is released during an infection site. IgM is also responsible for the initial activation of B-cells, macrophages and the complement system. It also makes up 7-10% of our total antibodies.
Which of the following statements is not correct regarding IgM antibod...
Understanding IgM Antibody
IgM is one of the five classes of antibodies (immunoglobulins) found in the human body, and it plays a crucial role in the immune response.
Key Characteristics of IgM
- Initial Activation of B-Cells:
IgM is primarily responsible for the initial activation of B-cells. When B-cells encounter an antigen, they often produce IgM antibodies first as part of the primary immune response.
- Effective Agglutination:
IgM antibodies are highly effective at agglutinating pathogens. Their pentameric structure allows them to bind multiple antigens simultaneously, enhancing their ability to clump and neutralize foreign invaders.
- Percentage of Total Antibodies:
IgM constitutes about 7-10% of the total antibodies in the bloodstream, making it a significant component of the immune system.
Why Option D is Incorrect
- Release Timing:
The statement that IgM is the last antibody to be released during the primary response is inaccurate. It is actually one of the first antibodies produced in response to an infection. IgM levels rise quickly within the first few days of exposure to an antigen, before any other antibody class, including IgG, starts to be produced.
Conclusion
Thus, the correct answer is option 'D', as it misrepresents the role of IgM in the immune response. IgM is not only the first antibody to be produced but also plays a vital role in the early defense against infections.