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The parent compound, 2-butanol, undergoes a set of reactions to produce compounds A and B. Which of the following statements accurately describes the absolute and relative configurations of the compounds in the reaction series below?
  • a)
    The relative configurations of A and B can be determined to be (R) and (S), while the absolute and relative configurations of the parent is already known
  • b)
    The relative configurations of the products are (-) and (+), while the absolute configuration of 2-butanol has to be determined.
  • c)
    The relative configurations of A and B can be determined to be (S) and (R), and the absolute configurations cannot be determined without further experimentation.
  • d)
    The absolute configurations of A and B can be determined to be (R) and (S), but the relative configurations cannot be determined without further experimentation.
Correct answer is option 'A'. Can you explain this answer?
Verified Answer
The parent compound, 2-butanol, undergoes a set of reactions to produc...
When 2-butanol is placed in pyridine with 4-toluenesulfonyl chloride, the alcohol is converted into the tosylate, which makes it a better leaving group. The reaction is known to occur with retention of configuration,here is no change in the stereochemistry.
When the tosylate is then placed into a sodium azide and ethanol solution, the azide acts as a nucleophile in a SN2 fashion to attack from the backside and substitute the tosylate with an azide group. There is an inversion of stereochemistry due to the backside attack.
2-butanol has a configuration of (R), so then compound A will have an (R) configuration and compound B an (S) configuration due to the inversion. These are our relative configurations of A and B.
Since we know the sign of rotation and the designation of R or S for the parent, we have its absolute configuration.
While for compounds A and B, without further experimentation, we do not ascertain whether R corresponds to (+) or (-). But, because you know the configuration of the starting alcohol, then the absolute configuration of the product is also known.
The answer is that the relative configurations of A and B can be determined to be (R) and (S), while the absolute and relative configurations of the parent is already known.
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Most Upvoted Answer
The parent compound, 2-butanol, undergoes a set of reactions to produc...
When 2-butanol is placed in pyridine with 4-toluenesulfonyl chloride, the alcohol is converted into the tosylate, which makes it a better leaving group. The reaction is known to occur with retention of configuration,here is no change in the stereochemistry.
When the tosylate is then placed into a sodium azide and ethanol solution, the azide acts as a nucleophile in a SN2 fashion to attack from the backside and substitute the tosylate with an azide group. There is an inversion of stereochemistry due to the backside attack.
2-butanol has a configuration of (R), so then compound A will have an (R) configuration and compound B an (S) configuration due to the inversion. These are our relative configurations of A and B.
Since we know the sign of rotation and the designation of R or S for the parent, we have its absolute configuration.
While for compounds A and B, without further experimentation, we do not ascertain whether R corresponds to (+) or (-). But, because you know the configuration of the starting alcohol, then the absolute configuration of the product is also known.
The answer is that the relative configurations of A and B can be determined to be (R) and (S), while the absolute and relative configurations of the parent is already known.
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The parent compound, 2-butanol, undergoes a set of reactions to produce compounds A and B. Which of the following statements accurately describes the absolute and relative configurations of the compounds in the reaction series below?a)The relative configurations of A and B can be determined to be (R) and (S), while the absolute and relative configurations of the parent is already knownb)The relative configurations of the products are (-) and (+), while the absolute configuration of 2-butanol has to be determined.c)The relative configurations of A and B can be determined to be (S) and (R), and the absolute configurations cannot be determined without further experimentation.d)The absolute configurations of A and B can be determined to be (R) and (S), but the relative configurations cannot be determined without further experimentation.Correct answer is option 'A'. Can you explain this answer? for MCAT 2025 is part of MCAT preparation. The Question and answers have been prepared according to the MCAT exam syllabus. Information about The parent compound, 2-butanol, undergoes a set of reactions to produce compounds A and B. Which of the following statements accurately describes the absolute and relative configurations of the compounds in the reaction series below?a)The relative configurations of A and B can be determined to be (R) and (S), while the absolute and relative configurations of the parent is already knownb)The relative configurations of the products are (-) and (+), while the absolute configuration of 2-butanol has to be determined.c)The relative configurations of A and B can be determined to be (S) and (R), and the absolute configurations cannot be determined without further experimentation.d)The absolute configurations of A and B can be determined to be (R) and (S), but the relative configurations cannot be determined without further experimentation.Correct answer is option 'A'. Can you explain this answer? covers all topics & solutions for MCAT 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for The parent compound, 2-butanol, undergoes a set of reactions to produce compounds A and B. Which of the following statements accurately describes the absolute and relative configurations of the compounds in the reaction series below?a)The relative configurations of A and B can be determined to be (R) and (S), while the absolute and relative configurations of the parent is already knownb)The relative configurations of the products are (-) and (+), while the absolute configuration of 2-butanol has to be determined.c)The relative configurations of A and B can be determined to be (S) and (R), and the absolute configurations cannot be determined without further experimentation.d)The absolute configurations of A and B can be determined to be (R) and (S), but the relative configurations cannot be determined without further experimentation.Correct answer is option 'A'. Can you explain this answer?.
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Here you can find the meaning of The parent compound, 2-butanol, undergoes a set of reactions to produce compounds A and B. Which of the following statements accurately describes the absolute and relative configurations of the compounds in the reaction series below?a)The relative configurations of A and B can be determined to be (R) and (S), while the absolute and relative configurations of the parent is already knownb)The relative configurations of the products are (-) and (+), while the absolute configuration of 2-butanol has to be determined.c)The relative configurations of A and B can be determined to be (S) and (R), and the absolute configurations cannot be determined without further experimentation.d)The absolute configurations of A and B can be determined to be (R) and (S), but the relative configurations cannot be determined without further experimentation.Correct answer is option 'A'. Can you explain this answer? defined & explained in the simplest way possible. Besides giving the explanation of The parent compound, 2-butanol, undergoes a set of reactions to produce compounds A and B. Which of the following statements accurately describes the absolute and relative configurations of the compounds in the reaction series below?a)The relative configurations of A and B can be determined to be (R) and (S), while the absolute and relative configurations of the parent is already knownb)The relative configurations of the products are (-) and (+), while the absolute configuration of 2-butanol has to be determined.c)The relative configurations of A and B can be determined to be (S) and (R), and the absolute configurations cannot be determined without further experimentation.d)The absolute configurations of A and B can be determined to be (R) and (S), but the relative configurations cannot be determined without further experimentation.Correct answer is option 'A'. Can you explain this answer?, a detailed solution for The parent compound, 2-butanol, undergoes a set of reactions to produce compounds A and B. Which of the following statements accurately describes the absolute and relative configurations of the compounds in the reaction series below?a)The relative configurations of A and B can be determined to be (R) and (S), while the absolute and relative configurations of the parent is already knownb)The relative configurations of the products are (-) and (+), while the absolute configuration of 2-butanol has to be determined.c)The relative configurations of A and B can be determined to be (S) and (R), and the absolute configurations cannot be determined without further experimentation.d)The absolute configurations of A and B can be determined to be (R) and (S), but the relative configurations cannot be determined without further experimentation.Correct answer is option 'A'. Can you explain this answer? has been provided alongside types of The parent compound, 2-butanol, undergoes a set of reactions to produce compounds A and B. Which of the following statements accurately describes the absolute and relative configurations of the compounds in the reaction series below?a)The relative configurations of A and B can be determined to be (R) and (S), while the absolute and relative configurations of the parent is already knownb)The relative configurations of the products are (-) and (+), while the absolute configuration of 2-butanol has to be determined.c)The relative configurations of A and B can be determined to be (S) and (R), and the absolute configurations cannot be determined without further experimentation.d)The absolute configurations of A and B can be determined to be (R) and (S), but the relative configurations cannot be determined without further experimentation.Correct answer is option 'A'. Can you explain this answer? theory, EduRev gives you an ample number of questions to practice The parent compound, 2-butanol, undergoes a set of reactions to produce compounds A and B. Which of the following statements accurately describes the absolute and relative configurations of the compounds in the reaction series below?a)The relative configurations of A and B can be determined to be (R) and (S), while the absolute and relative configurations of the parent is already knownb)The relative configurations of the products are (-) and (+), while the absolute configuration of 2-butanol has to be determined.c)The relative configurations of A and B can be determined to be (S) and (R), and the absolute configurations cannot be determined without further experimentation.d)The absolute configurations of A and B can be determined to be (R) and (S), but the relative configurations cannot be determined without further experimentation.Correct answer is option 'A'. Can you explain this answer? tests, examples and also practice MCAT tests.
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