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Repeated administration of some drugs will lead to a decrease in their effectiveness, an occurrence known as drug tolerance. When this occurs, doctors may need to increase the dosage in order to continue therapy. What is true of this increase?
  • a)
    Drugs of a certain type will exhibit the same drug tolerance rates
  • b)
    The dosage will increase by the same amount each time the patient reaches tolerance
  • c)
    The dosage increase is directly proportional to the initial dose
  • d)
    The increase in dosage will be the same for different patients
Correct answer is option 'C'. Can you explain this answer?
Most Upvoted Answer
Repeated administration of some drugs will lead to a decrease in their...
**Increase in Dosage for Drug Tolerance**
Drug tolerance is the phenomenon where the effectiveness of a drug decreases with repeated administration, leading to the need for higher dosages to achieve the same therapeutic effect. When doctors need to increase the dosage for a patient who has developed drug tolerance, the following points are important to consider:
**Proportional Increase in Dosage:**
- The increase in dosage required when a patient develops drug tolerance is directly proportional to the initial dose administered.
- This means that if a patient initially received a certain dose of a drug and then developed tolerance, the increase in dosage needed to maintain the therapeutic effect will be proportional to that initial dose.
**Example:**
- For example, if a patient initially received a dose of 100mg of a medication and developed tolerance, the increase in dosage needed might be 50% of the initial dose, resulting in a new dose of 150mg.
**Individual Variations:**
- It's important to note that the increase in dosage required for drug tolerance can vary among individuals.
- Factors such as metabolism, genetics, and the specific drug being used can all influence the extent of tolerance and the subsequent increase in dosage needed.
**Monitoring and Adjusting:**
- Doctors need to closely monitor patients who develop drug tolerance and adjust the dosage as needed to ensure that the therapeutic effect is maintained.
- Regular monitoring of patients' responses to medication and adjusting the dosage accordingly is essential in managing drug tolerance effectively.
In conclusion, the increase in dosage required for patients who develop drug tolerance is directly proportional to the initial dose administered. However, individual variations and careful monitoring are important considerations in managing drug tolerance effectively.
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Community Answer
Repeated administration of some drugs will lead to a decrease in their...
This statement suggests that the increase in dosage when drug tolerance occurs is directly proportional to the initial dose. However, this statement is not universally true for all drugs or situations. The dosage adjustment in response to drug tolerance can vary based on several factors, including the specific drug, individual patient response, and the therapeutic goals.
In some cases, the dosage increase may be proportional to the initial dose, especially if the drug's metabolism follows a linear pharmacokinetic profile. However, in other instances, the relationship may not be strictly proportional. Factors like saturation of drug metabolism pathways or receptor desensitization can affect the relationship between initial dose and subsequent dosage adjustments.
Therefore, while the dosage increase may sometimes be proportional to the initial dose, it is not a general rule that applies to all drugs and situations.
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Repeated administration of some drugs will lead to a decrease in their effectiveness, an occurrence known as drug tolerance. When this occurs, doctors may need to increase the dosage in order to continue therapy. What is true of this increase?a)Drugs of a certain type will exhibit the same drug tolerance ratesb)The dosage will increase by the same amount each time the patient reaches tolerancec)The dosage increase is directly proportional to the initial dosed)The increase in dosage will be the same for different patientsCorrect answer is option 'C'. Can you explain this answer? for MCAT 2025 is part of MCAT preparation. The Question and answers have been prepared according to the MCAT exam syllabus. Information about Repeated administration of some drugs will lead to a decrease in their effectiveness, an occurrence known as drug tolerance. When this occurs, doctors may need to increase the dosage in order to continue therapy. What is true of this increase?a)Drugs of a certain type will exhibit the same drug tolerance ratesb)The dosage will increase by the same amount each time the patient reaches tolerancec)The dosage increase is directly proportional to the initial dosed)The increase in dosage will be the same for different patientsCorrect answer is option 'C'. Can you explain this answer? covers all topics & solutions for MCAT 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Repeated administration of some drugs will lead to a decrease in their effectiveness, an occurrence known as drug tolerance. When this occurs, doctors may need to increase the dosage in order to continue therapy. What is true of this increase?a)Drugs of a certain type will exhibit the same drug tolerance ratesb)The dosage will increase by the same amount each time the patient reaches tolerancec)The dosage increase is directly proportional to the initial dosed)The increase in dosage will be the same for different patientsCorrect answer is option 'C'. Can you explain this answer?.
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