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Myelogenous leukemias are caused by the cancerous production of innate (non-specific) immune system cells: in which tissue is such production most likely to occur?
- a)Bone marrow
- b)Thymus
- c)Spleen
- d)Lymph nodes
Correct answer is option 'A'. Can you explain this answer?
Verified Answer
Myelogenous leukemias are caused by the cancerous production of innate...
Myelogenous leukemias, also known as myeloid leukemias, are cancers that arise from the abnormal growth and proliferation of myeloid cells in the bone marrow. The bone marrow is the primary site of production of myeloid cells, including granulocytes (neutrophils, eosinophils, basophils), monocytes, and platelets. In myelogenous leukemias, there is uncontrolled growth of these myeloid cells, leading to an overabundance of immature or abnormal cells in the bone marrow and peripheral blood. The abnormal production and accumulation of myeloid cells interfere with the normal function of the immune system.
Most Upvoted Answer
Myelogenous leukemias are caused by the cancerous production of innate...
Understanding Myelogenous Leukemias
Myelogenous leukemias are a type of cancer that arises from the uncontrolled proliferation of myeloid cells, which are part of the innate immune system. To understand why the bone marrow is the most likely site for this production, let’s delve into the roles of different tissues involved in hematopoiesis.
Bone Marrow: The Primary Site of Hematopoiesis
- The bone marrow is the primary site where all blood cells, including myeloid and lymphoid lineages, are produced.
- Myelogenous leukemias specifically involve myeloid cells, which include granulocytes, monocytes, erythrocytes, and platelets, all generated from hematopoietic stem cells in the bone marrow.
- In cases of myelogenous leukemia, mutations occur in the DNA of these progenitor cells, leading to the uncontrolled growth of myeloid lineage cells.
Other Tissues: Thymus, Spleen, and Lymph Nodes
- The thymus primarily functions in the maturation of T lymphocytes, not myeloid cells, making it irrelevant for myelogenous leukemias.
- The spleen and lymph nodes are involved in filtering blood and lymph, respectively, and play roles in the adaptive immune response, but they are not the sites of initial blood cell production.
- While these organs can be affected by leukemic cells as the disease progresses, they do not produce myelogenous leukemias.
Conclusion
In summary, the bone marrow is indeed the correct answer as it is the primary site where myeloid cells are produced and where the malignant transformation leading to myelogenous leukemias occurs.
Myelogenous leukemias are a type of cancer that arises from the uncontrolled proliferation of myeloid cells, which are part of the innate immune system. To understand why the bone marrow is the most likely site for this production, let’s delve into the roles of different tissues involved in hematopoiesis.
Bone Marrow: The Primary Site of Hematopoiesis
- The bone marrow is the primary site where all blood cells, including myeloid and lymphoid lineages, are produced.
- Myelogenous leukemias specifically involve myeloid cells, which include granulocytes, monocytes, erythrocytes, and platelets, all generated from hematopoietic stem cells in the bone marrow.
- In cases of myelogenous leukemia, mutations occur in the DNA of these progenitor cells, leading to the uncontrolled growth of myeloid lineage cells.
Other Tissues: Thymus, Spleen, and Lymph Nodes
- The thymus primarily functions in the maturation of T lymphocytes, not myeloid cells, making it irrelevant for myelogenous leukemias.
- The spleen and lymph nodes are involved in filtering blood and lymph, respectively, and play roles in the adaptive immune response, but they are not the sites of initial blood cell production.
- While these organs can be affected by leukemic cells as the disease progresses, they do not produce myelogenous leukemias.
Conclusion
In summary, the bone marrow is indeed the correct answer as it is the primary site where myeloid cells are produced and where the malignant transformation leading to myelogenous leukemias occurs.
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Myelogenous leukemias are caused by the cancerous production of innate (non-specific) immune system cells: in which tissue is such production most likely to occur?a)Bone marrowb)Thymusc)Spleend)Lymph nodesCorrect answer is option 'A'. Can you explain this answer? for MCAT 2025 is part of MCAT preparation. The Question and answers have been prepared according to the MCAT exam syllabus. Information about Myelogenous leukemias are caused by the cancerous production of innate (non-specific) immune system cells: in which tissue is such production most likely to occur?a)Bone marrowb)Thymusc)Spleend)Lymph nodesCorrect answer is option 'A'. Can you explain this answer? covers all topics & solutions for MCAT 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Myelogenous leukemias are caused by the cancerous production of innate (non-specific) immune system cells: in which tissue is such production most likely to occur?a)Bone marrowb)Thymusc)Spleend)Lymph nodesCorrect answer is option 'A'. Can you explain this answer?.
Myelogenous leukemias are caused by the cancerous production of innate (non-specific) immune system cells: in which tissue is such production most likely to occur?a)Bone marrowb)Thymusc)Spleend)Lymph nodesCorrect answer is option 'A'. Can you explain this answer? for MCAT 2025 is part of MCAT preparation. The Question and answers have been prepared according to the MCAT exam syllabus. Information about Myelogenous leukemias are caused by the cancerous production of innate (non-specific) immune system cells: in which tissue is such production most likely to occur?a)Bone marrowb)Thymusc)Spleend)Lymph nodesCorrect answer is option 'A'. Can you explain this answer? covers all topics & solutions for MCAT 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Myelogenous leukemias are caused by the cancerous production of innate (non-specific) immune system cells: in which tissue is such production most likely to occur?a)Bone marrowb)Thymusc)Spleend)Lymph nodesCorrect answer is option 'A'. Can you explain this answer?.
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