Where are voltage-gated sodium channels found in greatest concentration?a)In the axon terminalsb)In the trigger zonesc)In the dendritesd)In the nodes of RanvierCorrect answer is option 'B'. Can you explain this answer?

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Where are voltage-gated sodium channels found in greatest concentration?

a)
In the axon terminals
b)
In the trigger zones
c)
In the dendrites
d)
In the nodes of Ranvier

Correct answer is option 'B'. Can you explain this answer?

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Verified Answer

Where are voltage-gated sodium channels found in greatest concentratio...

Voltage-gated sodium channels are found in greatest concentration in the trigger zones of neurons. The trigger zones, which consist of the axon hillock and the initial segment of the axon, are responsible for generating and initiating action potentials. These areas have a high density of voltage-gated sodium channels, which are crucial for the rapid depolarization phase of an action potential.

When a graded potential reaches the trigger zone and reaches the threshold, voltage-gated sodium channels open, allowing an influx of sodium ions into the neuron. This depolarizes the membrane and generates an action potential that propagates along the axon.

While voltage-gated sodium channels are also present in other parts of the neuron, such as the axon terminals and nodes of Ranvier, their concentration is highest at the trigger zones, where the action potential is initiated. This localization ensures the efficient generation and propagation of action potentials along the axon.

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