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Guillain-Barre syndrome is an autoimmune disease which attack gangliosides, which are molecules found on the outside of a cell. Patients with this disease have a nerve conduction block which is often caused by a slowed conduction potential and can lead to paralysis. Which type of cell is attacked?
  • a)
    Schwann cells
  • b)
    Neurons
  • c)
    Astrocytes
  • d)
    Oligodendrocytes
Correct answer is option 'A'. Can you explain this answer?
Verified Answer
Guillain-Barre syndrome is an autoimmune disease which attack ganglios...
Guillain-Barre syndrome (GBS) is an autoimmune disease characterized by the immune system attacking the peripheral nerves. Specifically, it targets the myelin sheath, which is the protective covering around the nerve fibers. In GBS, the immune system mistakenly recognizes gangliosides, which are molecules found on the surface of cells, including Schwann cells.
Schwann cells are responsible for producing the myelin sheath in the peripheral nervous system. They wrap around the nerve fibers, providing insulation and aiding in the conduction of nerve impulses. When Schwann cells are attacked in GBS, the myelin sheath is damaged or destroyed, leading to a slowed or blocked conduction of nerve impulses.
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