The microglia arise from which embryonic layer?a)Endodermb)Ectodermc)Neural crestd)MesodermCorrect answer is option 'D'. Can you explain this answer?

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MCAT Exam > MCAT Questions > The microglia arise from which embryonic laye...

The microglia arise from which embryonic layer?

a)
Endoderm
b)
Ectoderm
c)
Neural crest
d)
Mesoderm

Correct answer is option 'D'. Can you explain this answer?

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Verified Answer

The microglia arise from which embryonic layer?a)Endodermb)Ectodermc)N...

Microglia, the resident immune cells of the central nervous system (CNS), originate from the mesoderm during embryonic development. The mesoderm is one of the primary germ layers formed during gastrulation. It gives rise to various structures, including muscle, connective tissue, blood vessels, and certain immune cells.

Microglia develop from myeloid progenitor cells that arise from the yolk sac and subsequently migrate into the developing CNS. Once in the CNS, these progenitor cells differentiate into microglia and take up residence in the brain and spinal cord.

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