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Which one of the following statement is INCORRECT for Z-DNA?
  • a)
    Left-handed DNA
  • b)
    Mostly found in alternating purine-pyrimidine sequences
  • c)
    Only one deep, narrow groove
  • d)
    Anti glycosidic bond conformation
Correct answer is option 'D'. Can you explain this answer?
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Verified Answer
Which one of the following statement is INCORRECT for Z-DNA?a)Left-han...
Anti glycosidic bond conformation is incorrect as in Z-DNA the sugar and glycosidic bond conformations alternate, anti for C and syn for G while in B form there is only anti glycosidic bond conformation.
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Which one of the following statement is INCORRECT for Z-DNA?a)Left-han...
Incorrect Statement for Z-DNA:
Z-DNA is a unique form of DNA with distinct structural features that differentiate it from the more common B-DNA. One of the statements provided is incorrect for Z-DNA:

Anti glycosidic bond conformation:
- The incorrect statement is that Z-DNA has an anti glycosidic bond conformation. In reality, Z-DNA actually has a syn glycosidic bond conformation. This means that the nucleotide bases are oriented in a way that allows for a syn conformation of the glycosidic bond between the sugar and the base.

Other Characteristics of Z-DNA:
- Left-handed DNA: Z-DNA is indeed a left-handed helical form of DNA, which is different from the more common right-handed B-DNA.
- Mostly found in alternating purine-pyrimidine sequences: Z-DNA is typically found in DNA sequences that alternate between purine (adenine and guanine) and pyrimidine (cytosine and thymine) bases.
- Only one deep, narrow groove: Z-DNA has a single deep, narrow major groove and a shallow minor groove, which is different from the major and minor groove combination found in B-DNA.
In conclusion, the incorrect statement about Z-DNA is that it has an anti glycosidic bond conformation, when in fact it has a syn glycosidic bond conformation.
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Which one of the following statement is INCORRECT for Z-DNA?a)Left-handed DNAb)Mostly found in alternating purine-pyrimidine sequencesc)Only one deep, narrow grooved)Anti glycosidic bond conformationCorrect answer is option 'D'. Can you explain this answer?
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