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Placenta accreta is a medical condition in which the placenta attaches abnormally to the myometrium. What is the earliest embryonic stage that this could occur, which cells are responsible for this attachment?
  • a)
    Blastulation, trophoblast
  • b)
    Early cleavage, trophoblast
  • c)
    Blastulation, epiblast
  • d)
    Early cleavage, embryoblast
Correct answer is option 'A'. Can you explain this answer?
Verified Answer
Placenta accreta is a medical condition in which the placenta attaches...
Placenta accreta is a condition where the placenta attaches abnormally to the myometrium, the muscular layer of the uterus. The attachment of the placenta occurs during the early stages of embryonic development.
In early embryonic development, after fertilization, the zygote undergoes cleavage, resulting in a solid ball of cells called the morula. Subsequently, the morula undergoes further cell division and forms a fluid-filled cavity called the blastocyst. The blastocyst consists of two main cell populations: the trophoblast and the inner cell mass (ICM).
The trophoblast is responsible for implantation and the subsequent formation of the placenta. It is the outer layer of cells in the blastocyst that interacts with the maternal tissues. The trophoblast differentiates into two distinct layers: the outer syncytiotrophoblast and the inner cytotrophoblast.
During blastulation, which is the process of blastocyst formation, the trophoblast cells play a crucial role in attaching the blastocyst to the uterine wall. The trophoblast cells invade and attach to the endometrium of the uterus, facilitating implantation.
Therefore, the earliest embryonic stage at which placenta accreta could occur is during blastulation, specifically during the attachment of trophoblast cells to the uterine wall.
The correct answer is option A: Blastulation, trophoblast.
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