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Which of the following would you expect to see in a cancerous mass?
  • a)
    Loss of function mutations in apoptosis-controlling proteins
  • b)
    Increased time in G0
  • c)
    Gain of function mutations in checkpoint proteins
  • d)
    Decreased ATP use
Correct answer is option 'A'. Can you explain this answer?
Verified Answer
Which of the following would you expect to see in a cancerous mass?a)L...
Loss of function mutations in apoptosis-controlling proteins can contribute to the formation of a cancerous mass. Apoptosis is a process of programmed cell death that helps eliminate damaged or abnormal cells. Mutations that disrupt the normal function of apoptosis-controlling proteins can prevent cells from undergoing apoptosis when necessary, allowing them to survive and accumulate, which can contribute to the formation of a tumor or cancerous mass.
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Which of the following would you expect to see in a cancerous mass?a)L...


Loss of function mutations in apoptosis-controlling proteins

Loss of function mutations in apoptosis-controlling proteins would be expected to see in a cancerous mass for the following reasons:

- Apoptosis resistance: Cancer cells often acquire mutations that inhibit the programmed cell death process, allowing them to survive and proliferate uncontrollably.
- Unregulated cell growth: Apoptosis-controlling proteins play a crucial role in regulating cell death. Mutations that disrupt this regulation can lead to uncontrolled cell growth, a hallmark of cancer.
- Survival advantages: By avoiding apoptosis, cancer cells can evade the body's natural defense mechanisms that would normally eliminate abnormal cells.

Overall, the presence of loss of function mutations in apoptosis-controlling proteins contributes to the development and progression of cancer by promoting cell survival and uncontrolled growth.
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