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The antibiotic doxycycline is known to bind and inhibit a particular ribosomal subunit to inhibit bacterial proliferation. How might this affect the 80S ribosome in human cells versus the 70S subunit in prokaryotes and why?
  • a)
    Doxycycline would inhibit human ribosome function by binding the 40S subunit, because both humans and prokaryotes share the 40S subunit
  • b)
    Doxycycline would inhibit human ribosome function by binding the 30S subunit, because both humans and prokaryotes share the 30S subunit
  • c)
    Doxycycline would not affect human ribosomes, because human ribosomes are made up of 60S and 40S subunits while prokaryotic ribosomes are made up of 50S and 30S subunits
  • d)
    Doxycycline would not affect human ribosomes, because human ribosomes are made up of 30S and 50S subunits while prokaryotic ribosomes are made up of 30S and 40S subunits
Correct answer is option 'C'. Can you explain this answer?
Most Upvoted Answer
The antibiotic doxycycline is known to bind and inhibit a particular r...
The correct answer is C. Doxycycline would not affect human ribosomes because human ribosomes are made up of 60S and 40S subunits, while prokaryotic ribosomes are made up of 50S and 30S subunits.
Doxycycline specifically targets the bacterial ribosome and inhibits protein synthesis by binding to the 30S subunit in prokaryotes. The binding of doxycycline interferes with the bacterial ribosome's ability to read and translate mRNA, thereby inhibiting bacterial proliferation.
In eukaryotes, such as human cells, ribosomes have a different structure. They are composed of a 60S large subunit and a 40S small subunit. Since the structure of human ribosomes is different from prokaryotic ribosomes, doxycycline does not bind to or affect human ribosomes. Therefore, doxycycline is selective for inhibiting bacterial protein synthesis while having little effect on human cells.
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The antibiotic doxycycline is known to bind and inhibit a particular ribosomal subunit to inhibit bacterial proliferation. How might this affect the 80S ribosome in human cells versus the 70S subunit in prokaryotes and why?a)Doxycycline would inhibit human ribosome function by binding the 40S subunit, because both humans and prokaryotes share the 40S subunitb)Doxycycline would inhibit human ribosome function by binding the 30S subunit, because both humans and prokaryotes share the 30S subunitc)Doxycycline would not affect human ribosomes, because human ribosomes are made up of 60S and 40S subunits while prokaryotic ribosomes are made up of 50S and 30S subunitsd)Doxycycline would not affect human ribosomes, because human ribosomes are made up of 30S and 50S subunits while prokaryotic ribosomes are made up of 30S and 40S subunitsCorrect answer is option 'C'. Can you explain this answer?
Question Description
The antibiotic doxycycline is known to bind and inhibit a particular ribosomal subunit to inhibit bacterial proliferation. How might this affect the 80S ribosome in human cells versus the 70S subunit in prokaryotes and why?a)Doxycycline would inhibit human ribosome function by binding the 40S subunit, because both humans and prokaryotes share the 40S subunitb)Doxycycline would inhibit human ribosome function by binding the 30S subunit, because both humans and prokaryotes share the 30S subunitc)Doxycycline would not affect human ribosomes, because human ribosomes are made up of 60S and 40S subunits while prokaryotic ribosomes are made up of 50S and 30S subunitsd)Doxycycline would not affect human ribosomes, because human ribosomes are made up of 30S and 50S subunits while prokaryotic ribosomes are made up of 30S and 40S subunitsCorrect answer is option 'C'. Can you explain this answer? for BMAT 2024 is part of BMAT preparation. The Question and answers have been prepared according to the BMAT exam syllabus. Information about The antibiotic doxycycline is known to bind and inhibit a particular ribosomal subunit to inhibit bacterial proliferation. How might this affect the 80S ribosome in human cells versus the 70S subunit in prokaryotes and why?a)Doxycycline would inhibit human ribosome function by binding the 40S subunit, because both humans and prokaryotes share the 40S subunitb)Doxycycline would inhibit human ribosome function by binding the 30S subunit, because both humans and prokaryotes share the 30S subunitc)Doxycycline would not affect human ribosomes, because human ribosomes are made up of 60S and 40S subunits while prokaryotic ribosomes are made up of 50S and 30S subunitsd)Doxycycline would not affect human ribosomes, because human ribosomes are made up of 30S and 50S subunits while prokaryotic ribosomes are made up of 30S and 40S subunitsCorrect answer is option 'C'. Can you explain this answer? covers all topics & solutions for BMAT 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for The antibiotic doxycycline is known to bind and inhibit a particular ribosomal subunit to inhibit bacterial proliferation. How might this affect the 80S ribosome in human cells versus the 70S subunit in prokaryotes and why?a)Doxycycline would inhibit human ribosome function by binding the 40S subunit, because both humans and prokaryotes share the 40S subunitb)Doxycycline would inhibit human ribosome function by binding the 30S subunit, because both humans and prokaryotes share the 30S subunitc)Doxycycline would not affect human ribosomes, because human ribosomes are made up of 60S and 40S subunits while prokaryotic ribosomes are made up of 50S and 30S subunitsd)Doxycycline would not affect human ribosomes, because human ribosomes are made up of 30S and 50S subunits while prokaryotic ribosomes are made up of 30S and 40S subunitsCorrect answer is option 'C'. Can you explain this answer?.
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