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Pyrimidine dimers resulting from UV light damage to DNA are removed from sequences via the action of what class of enzymes?
  • a)
    Polymerases
  • b)
    Helicases
  • c)
    Ligases
  • d)
    Endonucleases
Correct answer is option 'D'. Can you explain this answer?
Verified Answer
Pyrimidine dimers resulting from UV light damage to DNA are removed fr...
Pyrimidine dimers are a type of DNA damage that occurs when adjacent pyrimidine bases (thymine or cytosine) on the same DNA strand form covalent bonds with each other due to exposure to ultraviolet (UV) light. These dimers can distort the DNA structure and interfere with normal DNA replication and transcription.
To repair pyrimidine dimers, a class of enzymes called endonucleases is involved. Endonucleases are responsible for cleaving the damaged DNA strand at specific sites near the pyrimidine dimer. This creates a gap in the DNA molecule, allowing for the removal of the damaged section.
After the damaged DNA segment is removed, other DNA repair enzymes, such as DNA polymerases, helicases, and ligases, come into play to fill in the gap with new nucleotides and seal the DNA backbone, restoring the integrity of the DNA sequence.
However, specifically for the removal of pyrimidine dimers, it is the action of endonucleases that in
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