The results of a linkage analysis of genes A, B, C, and D have just come in from the lab. In what order are the alleles found on the chromosome?a)ABCDb)DCABc)CDABd)ACDBCorrect answer is option 'B'. Can you explain this answer?

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The results of a linkage analysis of genes A, B, C, and D have just come in from the lab. In what order are the alleles found on the chromosome?

a)
ABCD
b)
DCAB
c)
CDAB
d)
ACDB

Correct answer is option 'B'. Can you explain this answer?

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The results of a linkage analysis of genes A, B, C, and D have just co...

Based on the given recombination frequencies, we can determine the order of the alleles on the chromosome. The pairs with the lowest recombination frequencies are likely to be the closest together on the chromosome. Let's analyze the given recombination frequencies:

A/B: 3.0%
A/C: 5.0%
B/C: 8.0%
A/D: 8.0%
C/D: 3.0%

From these frequencies, we can conclude that the A and B alleles have the lowest recombination frequency, indicating that they are closest together. Similarly, the C and D alleles also have the lowest recombination frequency, suggesting that they are also closely linked.

Now let's consider the order of the alleles. Since A and B are closest together, they should be adjacent to each other on the chromosome. Similarly, C and D should be adjacent to each other.

Based on this information, the most likely order of the alleles on the chromosome is:

B - A - C - D

Therefore, option B (DCAB) is the most accurate representation of the order of alleles on the chromosome.

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