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A polypeptide chain contains two terminals – one carboxyl-terminal (C terminal) and the other amino-terminal (N terminal). Which of the following is true?
  • a)
    N terminal is synthesized last during translation
  • b)
    C terminal is synthesized first during translation
  • c)
    N terminal is represented on the right side and C terminal on the left side
  • d)
    N terminal is represented on the left side and C terminal on the right side
Correct answer is option 'D'. Can you explain this answer?
Verified Answer
A polypeptide chain contains two terminals – one carboxyl-termin...
During translation, the first amino acid attached has an amino free end and the last amino acid has a carboxyl free end. Hence, the N terminal is represented on the left side and C terminal on the right side.
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Most Upvoted Answer
A polypeptide chain contains two terminals – one carboxyl-termin...
Understanding Polypeptide Chains
A polypeptide chain is a sequence of amino acids linked by peptide bonds, and it has distinct ends: the amino-terminal (N terminal) and carboxyl-terminal (C terminal).
Translation Process
- During protein synthesis (translation), the ribosome assembles amino acids in a specific order.
- The synthesis begins at the N terminal and proceeds toward the C terminal.
Synthesis Directionality
- The N terminal is synthesized first, and thus it is represented on the left side of the polypeptide chain.
- The C terminal, being the last part synthesized, is found on the right side.
Visual Representation
- In a linear representation of a polypeptide:
- N terminal is on the left side (amino group, -NH2).
- C terminal is on the right side (carboxyl group, -COOH).
Correct Answer Explanation
- Therefore, the statement "N terminal is represented on the left side and C terminal on the right side" is correct.
- This understanding is crucial for interpreting protein structure and function, as the orientation plays a significant role in biochemical interactions.
In summary, the N terminal is always on the left, while the C terminal is on the right, which aligns with the synthesis direction in translation.
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A polypeptide chain contains two terminals – one carboxyl-terminal (C terminal) and the other amino-terminal (N terminal). Which of the following is true?a)N terminal is synthesized last during translationb)C terminal is synthesized first during translationc)N terminal is represented on the right side and C terminal on the left sided)N terminal is represented on the left side and C terminal on the right sideCorrect answer is option 'D'. Can you explain this answer? for MCAT 2025 is part of MCAT preparation. The Question and answers have been prepared according to the MCAT exam syllabus. Information about A polypeptide chain contains two terminals – one carboxyl-terminal (C terminal) and the other amino-terminal (N terminal). Which of the following is true?a)N terminal is synthesized last during translationb)C terminal is synthesized first during translationc)N terminal is represented on the right side and C terminal on the left sided)N terminal is represented on the left side and C terminal on the right sideCorrect answer is option 'D'. Can you explain this answer? covers all topics & solutions for MCAT 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for A polypeptide chain contains two terminals – one carboxyl-terminal (C terminal) and the other amino-terminal (N terminal). Which of the following is true?a)N terminal is synthesized last during translationb)C terminal is synthesized first during translationc)N terminal is represented on the right side and C terminal on the left sided)N terminal is represented on the left side and C terminal on the right sideCorrect answer is option 'D'. Can you explain this answer?.
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