cis-trans complementation testing is used to determine:a)if two mutations are allelic in natureb)If two genes interact with one anotherc)the number of genes influencing the phenotyped)to understand dominance/ recessive relations with allelesCorrect answer is option 'A'. Can you explain this answer?

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cis-trans complementation testing is used to determine:

a)
if two mutations are allelic in nature
b)
If two genes interact with one another
c)
the number of genes influencing the phenotype
d)
to understand dominance/ recessive relations with alleles

Correct answer is option 'A'. Can you explain this answer?

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cis-trans complementation testing is used to determine:a)if two mutati...

Concept:

The complementation test, also known as the cis-trans test, is a genetic test used to determine whether two mutations linked to a certain trait represent two distinct alleles of the same gene or two independent genes.
For recessive characteristics, the complementation test is relevant (traits normally not present in the phenotype due to masking by a dominant allele).
The complementation test can identify whether a recessive trait will be displayed in the following generation when two parent organisms each have two mutant genes in a homozygous recessive condition, leading to the expression of the recessive trait.
Because the heterozygote condition restores the function that would otherwise be lost in the homozygous recessive state, two mutations that occur in distinct genes are considered to be complementary.

Explanation:

The two essential elements of the test are known collectively as the cis-trans test.
The terms cis and trans describe the relationship between the two mutations; cis is used to refer to mutations that occur on the same chromosome and trans is used to refer to mutations that occur on different chromosomes.
The cis section of the complementation test entails making heterozygotes (one mutant chromosome and one wild-type, or normal, chromosome) such that one parent carries both mutations.
This procedure effectively serves as a control.
Whether both mutations are on the same gene or two separate genes, a functional protein is always produced in the cis test.
Making heterozygotes with unique mutations from various parents is required for the trans test.

Hence the correct answer is option 1

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cis-trans complementation testing is used to determine:a)if two mutations are allelic in natureb)If two genes interact with one anotherc)the number of genes influencing the phenotyped)to understand dominance/ recessive relations with allelesCorrect answer is option 'A'. Can you explain this answer?

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