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For continuation of protein synthesis in bacteria ribosomes need to be released from mRNA as well as  dissociate  into subunits  these processes do not occur simultaneously they need the following possible conditions
 A. RRF and EF-G in this process
 B. An intrinsic activity of ribosomes and uncharged tRNA required
 C. IF-1 promotes dissociation of ribosomes
 D. IF-1
and
 IF-3
promote this dissociation of ribosomes which of the following statements are correct
  • a)
    A and B
  • b)
    A and  C
  • c)
    B and  C
  • d)
    A and  D
Correct answer is option 'D'. Can you explain this answer?
Verified Answer
For continuation of protein synthesis in bacteria ribosomes need to be...
Concept:
  • Once the translation of an mRNA has been terminated and the completed polypeptide chain released, the ribosome must dissociate from the mRNA in order to be able to participate in a new round of protein synthesis.
Explanation:
  • For this i
    n addition to its role in the elongation cycle, EF-G also participates in dissociation of the 70S ribosome into 30S and 50S subunits following translation termination.
  • This is done in concert with ribosome recycling factor (RRF).
  • RRF binds to the ribosome with deacylated tRNA in the P/E state.                   
        
  • Following the action of EF-G, which requires hydrolysis of GTP and release of inorganic phosphate, the subunits dissociate and IF3 binds to the 30S subunit.
  • The presence of IF3 prevents reassociation of the 30S and 50S subunits and promotes the release of deacylated tRNA and mRNA prior to the formation of a translation initiation complex.
  • In mitochondria, two distinct EF-G proteins carry out translocation and recycling.
  • Although complexes of 70S ribosomes and RRF have been solved by X-ray crystallography, posttermination complexes with both RRF and EF-G have not.
  • IF1 stimulates the activities of IF3 and hence also the dissociation of the ribosomal subunits
Statement A: 
RRF and EF-G in this process
  •  Consider the explanation above thus this option is  true, as 
    EF-G and  ribosome recycling factor (RRF) perform this process
Statement B: 
An intrinsic activity of ribosomes and uncharged tRNA required.
  • Consider the explanation above thus this option is not true
Statement C: 
IF-1 promotes dissociation of ribosomes
  •  Consider the explanation above thus this option is not true
                        
Statement D: 
IF-1
and
 IF-3
promote this association of ribosomes
  •  Consider the explanation above thus this option is true, as 
    IF1 stimulates the activities of IF3 and hence also the dissociation of the ribosomal subunits
 
                     
hence the correct answer is option 1
                         
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Most Upvoted Answer
For continuation of protein synthesis in bacteria ribosomes need to be...
IF-1 and IF-3 promote dissociation of ribosomes:
IF-1 and IF-3 are initiation factors in bacteria that play a role in promoting the dissociation of ribosomes. When these factors are present, they help in releasing ribosomes from mRNA and dissociating them into subunits.

Conditions for ribosome release and dissociation:
- RRF and EF-G in this process: RRF (ribosome recycling factor) and EF-G (elongation factor G) are both involved in the recycling of ribosomes during translation. They work together to release ribosomes from mRNA and facilitate the dissociation process.
- IF-1 promotes dissociation of ribosomes: IF-1 is an initiation factor that helps in promoting the dissociation of ribosomes. It plays a role in releasing ribosomes from mRNA and facilitating the process of dissociation.
Therefore, the correct statement is option 'D' - A and D, as both A (RRF and EF-G) and D (IF-1 and IF-3) are involved in the processes required for the continuation of protein synthesis in bacteria.
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For continuation of protein synthesis in bacteria ribosomes need to be released from mRNA as well as dissociate into subunits these processes do not occur simultaneously they need the following possible conditions A. RRF and EF-G in this process B. An intrinsic activity of ribosomes and uncharged tRNA required C. IF-1 promotes dissociation of ribosomes D. IF-1 and IF-3 promote this dissociation of ribosomes which of the following statements are correcta)A and Bb)A and Cc)B and Cd)A and DCorrect answer is option 'D'. Can you explain this answer?
Question Description
For continuation of protein synthesis in bacteria ribosomes need to be released from mRNA as well as dissociate into subunits these processes do not occur simultaneously they need the following possible conditions A. RRF and EF-G in this process B. An intrinsic activity of ribosomes and uncharged tRNA required C. IF-1 promotes dissociation of ribosomes D. IF-1 and IF-3 promote this dissociation of ribosomes which of the following statements are correcta)A and Bb)A and Cc)B and Cd)A and DCorrect answer is option 'D'. Can you explain this answer? for Software Development 2025 is part of Software Development preparation. The Question and answers have been prepared according to the Software Development exam syllabus. Information about For continuation of protein synthesis in bacteria ribosomes need to be released from mRNA as well as dissociate into subunits these processes do not occur simultaneously they need the following possible conditions A. RRF and EF-G in this process B. An intrinsic activity of ribosomes and uncharged tRNA required C. IF-1 promotes dissociation of ribosomes D. IF-1 and IF-3 promote this dissociation of ribosomes which of the following statements are correcta)A and Bb)A and Cc)B and Cd)A and DCorrect answer is option 'D'. Can you explain this answer? covers all topics & solutions for Software Development 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for For continuation of protein synthesis in bacteria ribosomes need to be released from mRNA as well as dissociate into subunits these processes do not occur simultaneously they need the following possible conditions A. RRF and EF-G in this process B. An intrinsic activity of ribosomes and uncharged tRNA required C. IF-1 promotes dissociation of ribosomes D. IF-1 and IF-3 promote this dissociation of ribosomes which of the following statements are correcta)A and Bb)A and Cc)B and Cd)A and DCorrect answer is option 'D'. Can you explain this answer?.
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