NEET PG Exam > NEET PG Questions > Suicidal Enzyme is: (AIIMS May 2013)a)Lipoxyg...
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Suicidal Enzyme is: (AIIMS May 2013)
- a)Lipoxygenase
- b)Cyclooxygenase
- c)Thromboxane Synthase
- d)5' Nucleotidase
Correct answer is option 'B'. Can you explain this answer?
Most Upvoted Answer
Suicidal Enzyme is: (AIIMS May 2013)a)Lipoxygenaseb)Cyclooxygenasec)Th...
Cyclooxygenase is referred to as a 'suicide enzyme.' The deactivation of prostaglandin activity is partially due to an exceptional characteristic of cyclooxygenase, which is its ability for self-catalysed destruction; in other words, it acts as a 'suicide enzyme.' Quick overview of cyclooxygenase:
- Cyclooxygenase (COX), also known as prostaglandin H synthase
- Plays a role in the synthesis of prostanoids (prostaglandins, thromboxane, and prostacyclin)
- Exhibits two activities: cyclooxygenase and peroxidase
- Exists as two isoenzymes: COX-1 and COX-2
- NSAIDs:
- Aspirin: Inhibits both COX-1 and COX-2
- Indomethacin and ibuprofen: Inhibit cyclooxygenases by competing with arachidonate
- Coxibs: Selectively inhibit COX-2; however, some have been withdrawn or suspended from the market due to adverse side effects and safety concerns
- Completely inhibit the transcription of COX-2, but not COX-1
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Suicidal Enzyme is: (AIIMS May 2013)a)Lipoxygenaseb)Cyclooxygenasec)Thromboxane Synthased)5' NucleotidaseCorrect answer is option 'B'. Can you explain this answer? for NEET PG 2025 is part of NEET PG preparation. The Question and answers have been prepared according to the NEET PG exam syllabus. Information about Suicidal Enzyme is: (AIIMS May 2013)a)Lipoxygenaseb)Cyclooxygenasec)Thromboxane Synthased)5' NucleotidaseCorrect answer is option 'B'. Can you explain this answer? covers all topics & solutions for NEET PG 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Suicidal Enzyme is: (AIIMS May 2013)a)Lipoxygenaseb)Cyclooxygenasec)Thromboxane Synthased)5' NucleotidaseCorrect answer is option 'B'. Can you explain this answer?.
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