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The pKa values of lysine are 2.18, 8.95 and 10.79. The isoelectric point of lysine is _______
Correct answer is between '9,10'. Can you explain this answer?
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The pKa values of lysine are 2.18, 8.95 and 10.79. The isoelectric poi...
The isoelectric point (pI) of an amino acid is the pH at which the net charge on the molecule is zero. This occurs when the number of positive charges (from amino groups) is equal to the number of negative charges (from carboxyl groups). The pI of lysine can be calculated by averaging the two pKa values closest to the pI.
Calculation:
The two pKa values closest to the pI are 8.95 and 10.79. Therefore, the pI of lysine can be calculated as:
pI = (pKa1 + pKa2) / 2
pI = (8.95 + 10.79) / 2
pI = 9.87
Therefore, the isoelectric point of lysine is between 9 and 10.
Explanation of pKa values:
The pKa values of lysine represent the dissociation constants for the three ionizable groups in the molecule:
1. Carboxyl group (-COOH): pKa = 2.18
2. Alpha-amino group (-NH3+): pKa = 8.95
3. Side chain amino group (-NH3+): pKa = 10.79
At a pH below the pKa of a group, the group is protonated (has a positive charge). At a pH above the pKa of a group, the group is deprotonated (has a neutral or negative charge). The pKa values of lysine determine its charge and chemical properties at different pH values.
Calculation:
The two pKa values closest to the pI are 8.95 and 10.79. Therefore, the pI of lysine can be calculated as:
pI = (pKa1 + pKa2) / 2
pI = (8.95 + 10.79) / 2
pI = 9.87
Therefore, the isoelectric point of lysine is between 9 and 10.
Explanation of pKa values:
The pKa values of lysine represent the dissociation constants for the three ionizable groups in the molecule:
1. Carboxyl group (-COOH): pKa = 2.18
2. Alpha-amino group (-NH3+): pKa = 8.95
3. Side chain amino group (-NH3+): pKa = 10.79
At a pH below the pKa of a group, the group is protonated (has a positive charge). At a pH above the pKa of a group, the group is deprotonated (has a neutral or negative charge). The pKa values of lysine determine its charge and chemical properties at different pH values.
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The pKa values of lysine are 2.18, 8.95 and 10.79. The isoelectric poi...
PKb=(8.95+10.79) /2=9.87
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The pKa values of lysine are 2.18, 8.95 and 10.79. The isoelectric point of lysine is _______Correct answer is between '9,10'. Can you explain this answer?
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The pKa values of lysine are 2.18, 8.95 and 10.79. The isoelectric point of lysine is _______Correct answer is between '9,10'. Can you explain this answer? for Chemistry 2024 is part of Chemistry preparation. The Question and answers have been prepared according to the Chemistry exam syllabus. Information about The pKa values of lysine are 2.18, 8.95 and 10.79. The isoelectric point of lysine is _______Correct answer is between '9,10'. Can you explain this answer? covers all topics & solutions for Chemistry 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for The pKa values of lysine are 2.18, 8.95 and 10.79. The isoelectric point of lysine is _______Correct answer is between '9,10'. Can you explain this answer?.
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