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The transcription of b- galactosidase in the lac operon is inhibited when a more efficient source of such as glucose is present in the medium. This happens because
- a)Presence of glucose results in decreased concentration of intracellular Camp
- b)Presence Of excess lactose prevents glucose utilization
- c)Glucose binds to the lac operator and inhibits the operon
- d)The level of catabolite gene activator protein (CAP) goes down drastically
Correct answer is option 'A'. Can you explain this answer?
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The transcription of b- galactosidase in the lac operon is inhibited w...
Understanding the Lac Operon and Glucose Impact
The lac operon is a critical component of bacterial gene regulation that allows for the metabolism of lactose in the presence of glucose. When glucose is available, the expression of the lac operon is inhibited, primarily due to the effects of cyclic AMP (cAMP) levels.
Key Mechanism: cAMP Concentration
- Inhibition by Glucose: When glucose is present in the environment, it leads to a decrease in the intracellular concentration of cAMP.
- Role of cAMP: cAMP is essential for the activation of the catabolite activator protein (CAP), which binds to the promoter region of the lac operon to facilitate RNA polymerase binding and promote transcription.
Consequences of Low cAMP Levels
- Reduced CAP Activation: With lower cAMP levels, CAP cannot effectively bind to the lac promoter, resulting in reduced transcription of the lac operon genes, including b-galactosidase.
- Preference for Glucose: Bacteria preferentially utilize glucose due to its more efficient energy yield, thus repressing the expression of genes involved in lactose metabolism.
Summary of the Inhibition Process
- Presence of Glucose: Leads to decreased cAMP levels.
- Decreased cAMP: Results in reduced CAP activation.
- Consequential Effect: Lower transcription of the lac operon, inhibiting b-galactosidase production.
The understanding of this mechanism highlights how bacteria efficiently allocate resources based on available energy sources, prioritizing glucose over lactose.
The lac operon is a critical component of bacterial gene regulation that allows for the metabolism of lactose in the presence of glucose. When glucose is available, the expression of the lac operon is inhibited, primarily due to the effects of cyclic AMP (cAMP) levels.
Key Mechanism: cAMP Concentration
- Inhibition by Glucose: When glucose is present in the environment, it leads to a decrease in the intracellular concentration of cAMP.
- Role of cAMP: cAMP is essential for the activation of the catabolite activator protein (CAP), which binds to the promoter region of the lac operon to facilitate RNA polymerase binding and promote transcription.
Consequences of Low cAMP Levels
- Reduced CAP Activation: With lower cAMP levels, CAP cannot effectively bind to the lac promoter, resulting in reduced transcription of the lac operon genes, including b-galactosidase.
- Preference for Glucose: Bacteria preferentially utilize glucose due to its more efficient energy yield, thus repressing the expression of genes involved in lactose metabolism.
Summary of the Inhibition Process
- Presence of Glucose: Leads to decreased cAMP levels.
- Decreased cAMP: Results in reduced CAP activation.
- Consequential Effect: Lower transcription of the lac operon, inhibiting b-galactosidase production.
The understanding of this mechanism highlights how bacteria efficiently allocate resources based on available energy sources, prioritizing glucose over lactose.
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The transcription of b- galactosidase in the lac operon is inhibited when a more efficient source of such as glucose is present in the medium. This happens becausea)Presence of glucose results in decreased concentration of intracellular Campb)Presence Of excess lactose prevents glucose utilizationc)Glucose binds to the lac operator and inhibits the operond)The level of catabolite gene activator protein (CAP) goes down drasticallyCorrect answer is option 'A'. Can you explain this answer?
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The transcription of b- galactosidase in the lac operon is inhibited when a more efficient source of such as glucose is present in the medium. This happens becausea)Presence of glucose results in decreased concentration of intracellular Campb)Presence Of excess lactose prevents glucose utilizationc)Glucose binds to the lac operator and inhibits the operond)The level of catabolite gene activator protein (CAP) goes down drasticallyCorrect answer is option 'A'. Can you explain this answer? for IIT JAM 2024 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about The transcription of b- galactosidase in the lac operon is inhibited when a more efficient source of such as glucose is present in the medium. This happens becausea)Presence of glucose results in decreased concentration of intracellular Campb)Presence Of excess lactose prevents glucose utilizationc)Glucose binds to the lac operator and inhibits the operond)The level of catabolite gene activator protein (CAP) goes down drasticallyCorrect answer is option 'A'. Can you explain this answer? covers all topics & solutions for IIT JAM 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for The transcription of b- galactosidase in the lac operon is inhibited when a more efficient source of such as glucose is present in the medium. This happens becausea)Presence of glucose results in decreased concentration of intracellular Campb)Presence Of excess lactose prevents glucose utilizationc)Glucose binds to the lac operator and inhibits the operond)The level of catabolite gene activator protein (CAP) goes down drasticallyCorrect answer is option 'A'. Can you explain this answer?.
The transcription of b- galactosidase in the lac operon is inhibited when a more efficient source of such as glucose is present in the medium. This happens becausea)Presence of glucose results in decreased concentration of intracellular Campb)Presence Of excess lactose prevents glucose utilizationc)Glucose binds to the lac operator and inhibits the operond)The level of catabolite gene activator protein (CAP) goes down drasticallyCorrect answer is option 'A'. Can you explain this answer? for IIT JAM 2024 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about The transcription of b- galactosidase in the lac operon is inhibited when a more efficient source of such as glucose is present in the medium. This happens becausea)Presence of glucose results in decreased concentration of intracellular Campb)Presence Of excess lactose prevents glucose utilizationc)Glucose binds to the lac operator and inhibits the operond)The level of catabolite gene activator protein (CAP) goes down drasticallyCorrect answer is option 'A'. Can you explain this answer? covers all topics & solutions for IIT JAM 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for The transcription of b- galactosidase in the lac operon is inhibited when a more efficient source of such as glucose is present in the medium. This happens becausea)Presence of glucose results in decreased concentration of intracellular Campb)Presence Of excess lactose prevents glucose utilizationc)Glucose binds to the lac operator and inhibits the operond)The level of catabolite gene activator protein (CAP) goes down drasticallyCorrect answer is option 'A'. Can you explain this answer?.
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