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The decreasing order of isoelectric point for the following a-amino acids is:
(I) Lysine (II) Alanine (III) Glutamic acid
(I) Lysine (II) Alanine (III) Glutamic acid
- a)I > II > III
- b)II > I > III
- c)III > I > II
- d)I > III > II
Correct answer is option 'B'. Can you explain this answer?
Most Upvoted Answer
The decreasing order of isoelectric point for the following a-amino ac...
> (I) Lysine > (III) Glutamic acid > (II) Alanine
The isoelectric point (pI) is the pH at which an amino acid has a net charge of zero. The pI is determined by the presence of ionizable groups in the amino acid side chain and the amino and carboxyl groups of the peptide backbone.
Lysine has a pKₐ of 10.8 for its ε-amino group, which is the highest pKₐ value among the common amino acids. At a pH below its pI, lysine is positively charged due to the protonation of its amino group. At a pH above its pI, lysine is negatively charged due to the deprotonation of its carboxyl group. Therefore, the pI of lysine is higher than the pI of any other common amino acid.
Glutamic acid has a pKₐ of 4.3 for its carboxyl group and a pKₐ of 4.4 for its side chain carboxyl group. At a pH below its pI, glutamic acid is negatively charged due to the protonation of its amino group. At a pH above its pI, glutamic acid is positively charged due to the protonation of its carboxyl group. Therefore, the pI of glutamic acid is lower than the pI of lysine but higher than the pI of alanine.
Alanine has no ionizable groups in its side chain and has a pKₐ of 2.3 for its carboxyl group. At a pH below its pI, alanine is positively charged due to the protonation of its amino group. At a pH above its pI, alanine is negatively charged due to the deprotonation of its carboxyl group. Therefore, the pI of alanine is lower than the pI of both lysine and glutamic acid.
The isoelectric point (pI) is the pH at which an amino acid has a net charge of zero. The pI is determined by the presence of ionizable groups in the amino acid side chain and the amino and carboxyl groups of the peptide backbone.
Lysine has a pKₐ of 10.8 for its ε-amino group, which is the highest pKₐ value among the common amino acids. At a pH below its pI, lysine is positively charged due to the protonation of its amino group. At a pH above its pI, lysine is negatively charged due to the deprotonation of its carboxyl group. Therefore, the pI of lysine is higher than the pI of any other common amino acid.
Glutamic acid has a pKₐ of 4.3 for its carboxyl group and a pKₐ of 4.4 for its side chain carboxyl group. At a pH below its pI, glutamic acid is negatively charged due to the protonation of its amino group. At a pH above its pI, glutamic acid is positively charged due to the protonation of its carboxyl group. Therefore, the pI of glutamic acid is lower than the pI of lysine but higher than the pI of alanine.
Alanine has no ionizable groups in its side chain and has a pKₐ of 2.3 for its carboxyl group. At a pH below its pI, alanine is positively charged due to the protonation of its amino group. At a pH above its pI, alanine is negatively charged due to the deprotonation of its carboxyl group. Therefore, the pI of alanine is lower than the pI of both lysine and glutamic acid.
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The decreasing order of isoelectric point for the following a-amino ac...
Lysine 9.74, alanine 6.02, glutamic acid 3.22. answer is A.
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The decreasing order of isoelectric point for the following a-amino acids is:(I) Lysine (II) Alanine (III) Glutamic acida)I > II > IIIb)II > I > IIIc)III > I > IId)I > III > IICorrect answer is option 'B'. Can you explain this answer?
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The decreasing order of isoelectric point for the following a-amino acids is:(I) Lysine (II) Alanine (III) Glutamic acida)I > II > IIIb)II > I > IIIc)III > I > IId)I > III > IICorrect answer is option 'B'. Can you explain this answer? for Chemistry 2024 is part of Chemistry preparation. The Question and answers have been prepared according to the Chemistry exam syllabus. Information about The decreasing order of isoelectric point for the following a-amino acids is:(I) Lysine (II) Alanine (III) Glutamic acida)I > II > IIIb)II > I > IIIc)III > I > IId)I > III > IICorrect answer is option 'B'. Can you explain this answer? covers all topics & solutions for Chemistry 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for The decreasing order of isoelectric point for the following a-amino acids is:(I) Lysine (II) Alanine (III) Glutamic acida)I > II > IIIb)II > I > IIIc)III > I > IId)I > III > IICorrect answer is option 'B'. Can you explain this answer?.
The decreasing order of isoelectric point for the following a-amino acids is:(I) Lysine (II) Alanine (III) Glutamic acida)I > II > IIIb)II > I > IIIc)III > I > IId)I > III > IICorrect answer is option 'B'. Can you explain this answer? for Chemistry 2024 is part of Chemistry preparation. The Question and answers have been prepared according to the Chemistry exam syllabus. Information about The decreasing order of isoelectric point for the following a-amino acids is:(I) Lysine (II) Alanine (III) Glutamic acida)I > II > IIIb)II > I > IIIc)III > I > IId)I > III > IICorrect answer is option 'B'. Can you explain this answer? covers all topics & solutions for Chemistry 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for The decreasing order of isoelectric point for the following a-amino acids is:(I) Lysine (II) Alanine (III) Glutamic acida)I > II > IIIb)II > I > IIIc)III > I > IId)I > III > IICorrect answer is option 'B'. Can you explain this answer?.
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The decreasing order of isoelectric point for the following a-amino acids is:(I) Lysine (II) Alanine (III) Glutamic acida)I > II > IIIb)II > I > IIIc)III > I > IId)I > III > IICorrect answer is option 'B'. Can you explain this answer?, a detailed solution for The decreasing order of isoelectric point for the following a-amino acids is:(I) Lysine (II) Alanine (III) Glutamic acida)I > II > IIIb)II > I > IIIc)III > I > IId)I > III > IICorrect answer is option 'B'. Can you explain this answer? has been provided alongside types of The decreasing order of isoelectric point for the following a-amino acids is:(I) Lysine (II) Alanine (III) Glutamic acida)I > II > IIIb)II > I > IIIc)III > I > IId)I > III > IICorrect answer is option 'B'. Can you explain this answer? theory, EduRev gives you an
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