Symbols used: P (partial pressure), I (inspired air), E (expired air), A (alveolar), a (arterial), v (venous), v̅ (mixed venous). For example, PIO₂ is the partial pressure of O₂ in inspired air.
Composition of Atmospheric and Alveolar Gases:
Oxygen transport from lungs to tissues occurs via blood circulation and diffusion along a concentration gradient, represented by PO2 differences:
Uptake of oxygen by pulmonary blood:
Transport of oxygen in arterial blood:
Oxygen is transported in two forms:
Total O₂ in 100 mL blood:
Release of oxygen to tissues:
Respiratory Exchange Ratio
Bohr Effect:
Effect of pH:
Temperature:
2,3-Diphosphoglycerate (2,3-DPG):
DPG Level with Blood Storage:
Abnormal Forms of Hemoglobin:
Carboxyhemoglobin (HbCO):
Myoglobin:
Factors Causing OHDC Shifts:
Four Categories of Hypoxia (Table 10.8):
Cyanosis
40 docs|9 tests
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1. What is the difference between perfusion-limited and diffusion-limited gas exchange? | ![]() |
2. How is the diffusing capacity of the respiratory membrane measured? | ![]() |
3. What are the primary mechanisms of oxygen transport in the blood? | ![]() |
4. What is the significance of the oxyhemoglobin dissociation curve (OHDC)? | ![]() |
5. What are the different ways carbon dioxide is transported in the blood? | ![]() |