In 180, the world was undergoing significant changes and historical events. Here are some notable events that occurred in that year:

1. The Roman Empire was at its peak under the rule of Emperor Marcus Aurelius.

2. The Antonine Plague, also known as the Plague of Galen, broke out in the Roman Empire, causing significant disruption and mortality.

3. The construction of the Colosseum in Rome was completed, becoming the largest amphitheater ever built.

4. The Chinese Han Dynasty was in decline, leading to the Three Kingdoms period in China.

5. The Gupta Empire in India was flourishing, establishing itself as a major power in South Asia.

6. The Fugitive Slave Act was passed in the United States, allowing slave owners to recapture escaped slaves in any state or territory.

7. The Napoleonic Wars were ongoing, with France under the rule of Napoleon Bonaparte expanding its empire across Europe.

8. The United Kingdom abolished the slave trade, but not slavery itself.

9. Ludwig van Beethoven composed his Symphony No. 1, marking the beginning of his career as a renowned composer.

10. The Lewis and Clark Expedition, also known as the Corps of Discovery, began its exploration of the western United States.

These are just a few examples of the many significant events and developments that occurred in 180.