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Which of the following molecules produces highest energy on breakdown of its high energy bond
  • a)
    ATP
  • b)
    Acetyl CoA
  • c)
    PEP   
  • d)
    ADP
Correct answer is option 'C'. Can you explain this answer?
Verified Answer
Which of the following molecules produces highest energy on breakdown ...
ATP produces high amount of energy, yet it is not the highest free energy molecule. The free energy of ATP hydrolysis is – 30 kJ per mole, while PEP has much higher energy of breakdown i.e. ~ 54 kJ per mole.
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Which of the following molecules produces highest energy on breakdown ...
Explanation:
In cellular metabolism, ATP (adenosine triphosphate) is the primary molecule used for energy storage and transfer. When ATP is hydrolyzed, it releases energy by breaking the high-energy bond between the second and third phosphate groups. However, in terms of the highest energy released on breakdown of its high-energy bond, PEP (phosphoenolpyruvate) is the molecule that produces the highest energy.

ATP:
- ATP is composed of three phosphate groups, a ribose sugar, and an adenine base.
- The bond between the second and third phosphate groups is a high-energy bond, known as a phosphoanhydride bond.
- When ATP is hydrolyzed, it is converted into ADP (adenosine diphosphate) and inorganic phosphate (Pi), and energy is released.
- The energy released from the breakdown of ATP is utilized by cells for various cellular processes.

Acetyl CoA:
- Acetyl CoA is an important molecule in cellular metabolism as it is the entry point for the citric acid cycle (also known as the Krebs cycle or TCA cycle).
- Acetyl CoA is formed from the breakdown of carbohydrates, fats, and proteins.
- While the breakdown of acetyl CoA releases energy, it does not involve the hydrolysis of a high-energy bond like ATP or PEP.

PEP:
- PEP is an intermediate molecule in glycolysis, the metabolic pathway that converts glucose into pyruvate.
- PEP is formed from the conversion of phosphoenolpyruvate carboxykinase in the presence of ATP.
- The breakdown of PEP involves the transfer of a phosphate group to ADP, forming ATP and pyruvate.
- This transfer of the phosphate group from PEP to ADP releases a significant amount of energy, making it the molecule that produces the highest energy on breakdown of its high-energy bond.

ADP:
- ADP is the molecule formed after the hydrolysis of ATP.
- While the breakdown of ADP releases energy, it does not involve the hydrolysis of a high-energy bond like ATP or PEP.

Conclusion:
In summary, while ATP is the primary molecule used for energy storage and transfer in cellular metabolism, PEP is the molecule that produces the highest energy on breakdown of its high-energy bond. The hydrolysis of PEP releases a significant amount of energy due to the transfer of a phosphate group to ADP, forming ATP and pyruvate.
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Community Answer
Which of the following molecules produces highest energy on breakdown ...
Phospho enol pyruvic acid
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Which of the following molecules produces highest energy on breakdown of its high energy bonda)ATPb)Acetyl CoAc)PEP d)ADPCorrect answer is option 'C'. Can you explain this answer?
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