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H-DNA is also known as hoogsteen DNA, which is known to contain triple helical structure, due to a special type of pairing called hoogsteen pairing between base pairs. Which of the following statement is true in this context
- a)Hoogsteen DNA is found only in prokaryotes
- b)Hoogsteen pairing is caused by flipping of purines from anti to syn form
- c)Hoogsteen DNA is half or single stranded DNA molecule.
- d)Hoogsteen faces and watson crick faces are opposite on a nucleotide
Correct answer is option 'B,D'. Can you explain this answer?
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H-DNA is also known as hoogsteen DNA, which is known to contain triple...
Hoogsteen DNA and Hoogsteen pairing:
Hoogsteen DNA, also known as H-DNA, is a non-B form of DNA that can adopt a triple helical structure. It is named after its discoverer, Karst Hoogsteen. This unique structure is formed due to a special type of base pairing called Hoogsteen pairing.
Hoogsteen pairing:
Hoogsteen pairing involves the flipping of purine bases (adenine or guanine) from their usual anti conformation to syn conformation. In the syn conformation, the purine base rotates by 180 degrees around the glycosidic bond, resulting in a different hydrogen bonding pattern. In the Hoogsteen pairing, the purine base forms hydrogen bonds with another base in the DNA strand, resulting in the formation of a triple helical structure.
True statements:
B) Hoogsteen pairing is caused by flipping of purines from anti to syn form:
The correct answer option is B because Hoogsteen pairing is indeed caused by the flipping of purines from their anti conformation to a syn conformation. This altered conformation allows the purine base to form additional hydrogen bonds with another base in the DNA strand.
D) Hoogsteen faces and Watson-Crick faces are opposite on a nucleotide:
The correct answer option is D because Hoogsteen faces and Watson-Crick faces are indeed opposite on a nucleotide. A nucleotide has two faces: the Hoogsteen face and the Watson-Crick face. The Hoogsteen face is the side of the purine base where the new hydrogen bonds are formed due to Hoogsteen pairing, while the Watson-Crick face is the side where the traditional hydrogen bonds are formed.
Incorrect statements:
A) Hoogsteen DNA is found only in prokaryotes:
This statement is incorrect. Hoogsteen DNA is not limited to prokaryotes; it can also be found in eukaryotes. Hoogsteen DNA has been observed in various organisms, including humans.
C) Hoogsteen DNA is half or single-stranded DNA molecule:
This statement is incorrect. Hoogsteen DNA is not necessarily half or single-stranded. It can exist as double-stranded DNA but with a non-B form triple helical structure due to Hoogsteen pairing. The triple helical structure can involve one strand in the Hoogsteen conformation and two strands in the anti conformation, or all three strands in the Hoogsteen conformation.
In conclusion, the true statements in this context are that Hoogsteen pairing is caused by flipping of purines from anti to syn form (option B) and Hoogsteen faces and Watson-Crick faces are opposite on a nucleotide (option D).
Hoogsteen DNA, also known as H-DNA, is a non-B form of DNA that can adopt a triple helical structure. It is named after its discoverer, Karst Hoogsteen. This unique structure is formed due to a special type of base pairing called Hoogsteen pairing.
Hoogsteen pairing:
Hoogsteen pairing involves the flipping of purine bases (adenine or guanine) from their usual anti conformation to syn conformation. In the syn conformation, the purine base rotates by 180 degrees around the glycosidic bond, resulting in a different hydrogen bonding pattern. In the Hoogsteen pairing, the purine base forms hydrogen bonds with another base in the DNA strand, resulting in the formation of a triple helical structure.
True statements:
B) Hoogsteen pairing is caused by flipping of purines from anti to syn form:
The correct answer option is B because Hoogsteen pairing is indeed caused by the flipping of purines from their anti conformation to a syn conformation. This altered conformation allows the purine base to form additional hydrogen bonds with another base in the DNA strand.
D) Hoogsteen faces and Watson-Crick faces are opposite on a nucleotide:
The correct answer option is D because Hoogsteen faces and Watson-Crick faces are indeed opposite on a nucleotide. A nucleotide has two faces: the Hoogsteen face and the Watson-Crick face. The Hoogsteen face is the side of the purine base where the new hydrogen bonds are formed due to Hoogsteen pairing, while the Watson-Crick face is the side where the traditional hydrogen bonds are formed.
Incorrect statements:
A) Hoogsteen DNA is found only in prokaryotes:
This statement is incorrect. Hoogsteen DNA is not limited to prokaryotes; it can also be found in eukaryotes. Hoogsteen DNA has been observed in various organisms, including humans.
C) Hoogsteen DNA is half or single-stranded DNA molecule:
This statement is incorrect. Hoogsteen DNA is not necessarily half or single-stranded. It can exist as double-stranded DNA but with a non-B form triple helical structure due to Hoogsteen pairing. The triple helical structure can involve one strand in the Hoogsteen conformation and two strands in the anti conformation, or all three strands in the Hoogsteen conformation.
In conclusion, the true statements in this context are that Hoogsteen pairing is caused by flipping of purines from anti to syn form (option B) and Hoogsteen faces and Watson-Crick faces are opposite on a nucleotide (option D).
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H-DNA is also known as hoogsteen DNA, which is known to contain triple...
Statement b and d are correct as the formation of H-DNA occurs due to flipping of purines from anti-orientation to syn orientation. As the hoogsteen and watson-crick faces are opposite to each other flipping of one of the base results in new possibilities of hydrogen bond formation. This allows the formation of hydrogen bonds such C…G…...C instead of conventional CG pairing. This allows the formation of triple helical DNA or tetra helical DNA.
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H-DNA is also known as hoogsteen DNA, which is known to contain triple helical structure, due to a special type of pairing called hoogsteen pairing between base pairs. Which of the following statement is true in this contexta)Hoogsteen DNA is found only in prokaryotesb)Hoogsteen pairing is caused by flipping of purines from anti to syn formc)Hoogsteen DNA is half or single stranded DNA molecule.d)Hoogsteen faces and watson crick faces are opposite on a nucleotideCorrect answer is option 'B,D'. Can you explain this answer?
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H-DNA is also known as hoogsteen DNA, which is known to contain triple helical structure, due to a special type of pairing called hoogsteen pairing between base pairs. Which of the following statement is true in this contexta)Hoogsteen DNA is found only in prokaryotesb)Hoogsteen pairing is caused by flipping of purines from anti to syn formc)Hoogsteen DNA is half or single stranded DNA molecule.d)Hoogsteen faces and watson crick faces are opposite on a nucleotideCorrect answer is option 'B,D'. Can you explain this answer? for IIT JAM 2024 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about H-DNA is also known as hoogsteen DNA, which is known to contain triple helical structure, due to a special type of pairing called hoogsteen pairing between base pairs. Which of the following statement is true in this contexta)Hoogsteen DNA is found only in prokaryotesb)Hoogsteen pairing is caused by flipping of purines from anti to syn formc)Hoogsteen DNA is half or single stranded DNA molecule.d)Hoogsteen faces and watson crick faces are opposite on a nucleotideCorrect answer is option 'B,D'. Can you explain this answer? covers all topics & solutions for IIT JAM 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for H-DNA is also known as hoogsteen DNA, which is known to contain triple helical structure, due to a special type of pairing called hoogsteen pairing between base pairs. Which of the following statement is true in this contexta)Hoogsteen DNA is found only in prokaryotesb)Hoogsteen pairing is caused by flipping of purines from anti to syn formc)Hoogsteen DNA is half or single stranded DNA molecule.d)Hoogsteen faces and watson crick faces are opposite on a nucleotideCorrect answer is option 'B,D'. Can you explain this answer?.
H-DNA is also known as hoogsteen DNA, which is known to contain triple helical structure, due to a special type of pairing called hoogsteen pairing between base pairs. Which of the following statement is true in this contexta)Hoogsteen DNA is found only in prokaryotesb)Hoogsteen pairing is caused by flipping of purines from anti to syn formc)Hoogsteen DNA is half or single stranded DNA molecule.d)Hoogsteen faces and watson crick faces are opposite on a nucleotideCorrect answer is option 'B,D'. Can you explain this answer? for IIT JAM 2024 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about H-DNA is also known as hoogsteen DNA, which is known to contain triple helical structure, due to a special type of pairing called hoogsteen pairing between base pairs. Which of the following statement is true in this contexta)Hoogsteen DNA is found only in prokaryotesb)Hoogsteen pairing is caused by flipping of purines from anti to syn formc)Hoogsteen DNA is half or single stranded DNA molecule.d)Hoogsteen faces and watson crick faces are opposite on a nucleotideCorrect answer is option 'B,D'. Can you explain this answer? covers all topics & solutions for IIT JAM 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for H-DNA is also known as hoogsteen DNA, which is known to contain triple helical structure, due to a special type of pairing called hoogsteen pairing between base pairs. Which of the following statement is true in this contexta)Hoogsteen DNA is found only in prokaryotesb)Hoogsteen pairing is caused by flipping of purines from anti to syn formc)Hoogsteen DNA is half or single stranded DNA molecule.d)Hoogsteen faces and watson crick faces are opposite on a nucleotideCorrect answer is option 'B,D'. Can you explain this answer?.
Solutions for H-DNA is also known as hoogsteen DNA, which is known to contain triple helical structure, due to a special type of pairing called hoogsteen pairing between base pairs. Which of the following statement is true in this contexta)Hoogsteen DNA is found only in prokaryotesb)Hoogsteen pairing is caused by flipping of purines from anti to syn formc)Hoogsteen DNA is half or single stranded DNA molecule.d)Hoogsteen faces and watson crick faces are opposite on a nucleotideCorrect answer is option 'B,D'. Can you explain this answer? in English & in Hindi are available as part of our courses for IIT JAM.
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