Correct statement/s is/are:a)Thymine is 3-methyl Uracilb)Watson and Cr...
Statement Analysis:
a) Thymine is 3-methyl Uracil - This statement is incorrect. Thymine and Uracil are two different nitrogenous bases found in DNA and RNA, respectively. Thymine is not a methylated form of Uracil.
b) Watson and Crick concluded that DNA consists of two strands of nucleotides with the sugar Phosphate backbone on inside and bases on outside - This statement is correct. According to the Watson-Crick model of DNA, the two strands of DNA are arranged in an anti-parallel manner, with the sugar-phosphate backbone on the inside and the nitrogenous bases (Adenine, Thymine, Guanine, and Cytosine) on the outside, forming hydrogen bonds between complementary base pairs.
c) Chargaff's rules state that DNA from any cell of any organism should have a 1:1 ratio (base Pair Rule) of A and T bases - This statement is correct. Erwin Chargaff discovered that the amount of Adenine (A) is equal to the amount of Thymine (T) and the amount of Guanine (G) is equal to the amount of Cytosine (C) in DNA. This is known as Chargaff's rules or the base pair rule.
d) AUG is used as a start codon during protein synthesis in the Translation Process - This statement is correct. AUG is the start codon in mRNA that signals the initiation of protein synthesis. It codes for the amino acid Methionine. The start codon AUG is recognized by the initiation complex (composed of the small ribosomal subunit, initiator tRNA, and initiation factors), which then recruits the large ribosomal subunit to begin translation.
Explanation:
- Watson and Crick's Model: In 1953, James Watson and Francis Crick proposed the double helix structure of DNA based on X-ray crystallography data obtained by Rosalind Franklin and Maurice Wilkins. Their model showed that DNA consists of two strands of nucleotides twisted around each other in a helical structure. The sugar-phosphate backbone forms the outer edges of the helix, while the nitrogenous bases project inward and form complementary base pairs. Adenine (A) pairs with Thymine (T) and Guanine (G) pairs with Cytosine (C) through hydrogen bonding. This model provided an explanation for DNA replication and the storage of genetic information.
- Chargaff's Rules: In the late 1940s, Erwin Chargaff discovered that the amounts of Adenine (A) and Thymine (T) in DNA are always equal, as are the amounts of Guanine (G) and Cytosine (C). This observation led to Chargaff's rules, which state that in any DNA molecule, the amount of A is equal to T, and the amount of G is equal to C. This is known as the base pair rule and is a fundamental principle of DNA structure and replication. Chargaff's rules played a crucial role in the understanding of DNA structure and the development of the Watson-Crick model.
- Start Codon AUG: The start codon AUG is the initiation codon for protein synthesis during translation. It codes for the amino acid Methionine (Met