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Which of the following proteins moves along a dsDNA, unwinds the strands ahead and degrade them, during homologous recombination is
  • a)
    RecA
  • b)
    RecBCD
  • c)
    RuvC
  • d)
    Chi
Correct answer is option 'B'. Can you explain this answer?
Verified Answer
Which of the following proteins moves along a dsDNA, unwinds the stran...
Rec BCD is an enzyme which initiates recombinational repair, wherever there is double stranded break in DNA. RecBCD acts both as a helicase, which separates the two strands of DNA and nuclease which makes single stranded nicks in DNA. RecA is then recruited on to these single stranded nicks which proceed with the repair.
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Most Upvoted Answer
Which of the following proteins moves along a dsDNA, unwinds the stran...
RecBCD
RecBCD is a protein complex involved in homologous recombination, specifically during the process of DNA repair. Here is how RecBCD functions during homologous recombination:

Moves along a dsDNA
- RecBCD is a helicase enzyme that moves along the double-stranded DNA molecule.

Unwinds the strands ahead
- As RecBCD moves along the DNA, it unwinds the strands ahead of it, creating single-stranded DNA regions.

Degrades the unwound DNA
- RecBCD also has nuclease activity, meaning it can degrade the single-stranded DNA regions that it creates. This degradation helps to generate the necessary DNA ends for the recombination process.
Therefore, RecBCD plays a crucial role in homologous recombination by unwinding and degrading DNA strands, ultimately facilitating the exchange of genetic material between homologous chromosomes.
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Which of the following proteins moves along a dsDNA, unwinds the strands ahead and degrade them, during homologous recombination isa)RecAb)RecBCDc)RuvCd)ChiCorrect answer is option 'B'. Can you explain this answer?
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