A mole of atoms refers to a specific quantity of atoms. It is defined as Avogadro's number (6.022 x 10^23) of atoms. This is equivalent to the atomic mass of an element expressed in grams.

The term "mole" is used to express the amount of a substance in chemistry. It is a unit of measurement that allows scientists to work with large quantities of atoms or molecules in a more convenient way.

The main difference between a mole of atoms and individual atoms is the quantity. A mole represents a fixed number of atoms (or molecules), while individual atoms refer to single particles. For example, if you have a mole of carbon atoms, you would have 6.022 x 10^23 carbon atoms. Each carbon atom is an individual unit, but when you have a mole, you have a huge number of them.

Additionally, a mole of atoms is a macroscopic quantity, meaning it is measurable at the macroscopic scale. It provides a way to relate the microscopic world of atoms to the macroscopic world of everyday objects and substances.