Solution:

The given sequence is: 4, 12, 36, ?, 324

To find the missing term, let's analyze the given sequence.

1. Difference between first two terms:

The difference between the first two terms is 12 - 4 = 8.

2. Difference between second two terms:

The difference between the second two terms is 36 - 12 = 24.

3. Difference between third two terms:

The difference between the third two terms is ? - 36.

4. Difference between fourth two terms:

The difference between the fourth two terms is 324 - ?.

If we observe the differences between the terms, we can see that the differences are increasing in multiples of 3.

So, the difference between the third two terms is 24 + 3 = 27.

Therefore, the missing term can be found by adding 27 to the third term, which is 36.

Hence, the missing term is 36 + 27 = 63.

Therefore, the correct answer is not given in the options.

Note: This question may have an error in the options provided.