Directions: In the following questions, A statement of Assertion (A) ...
Assertion (A) Explained
The assertion states that aromatic 1° amines can be prepared by Gabriel Phthalimide synthesis.
- This statement is true.
- The Gabriel Phthalimide synthesis is a method used to prepare primary amines, particularly aromatic amines, by the nucleophilic substitution of phthalimide's anion with an alkyl halide.
Reason (R) Explained
The reason given is that aryl halides do not undergo nucleophilic substitution with the anion formed by phthalimide.
- This statement is also true.
- Aryl halides are generally resistant to nucleophilic substitution reactions due to the stability of the aromatic ring, which makes it less likely for a nucleophile (like the anion from phthalimide) to attack the carbon attached to the halide.
Conclusion on A and R
- While both A and R are true, R does not provide a correct explanation for A.
- The Gabriel synthesis does work for preparing aromatic 1° amines, even though aryl halides do not allow direct nucleophilic substitution. Instead, the process involves forming the anion from phthalimide and using it to react with a suitable alkyl halide to create an intermediate, which can then be hydrolyzed to yield the aromatic amine.
Final Answer
Therefore, the correct choice is option D: A is false and R is true.
Directions: In the following questions, A statement of Assertion (A) ...
Aromatic 1° amines cannot be prepared by Gabriel Phthalimide synthesis because aryl halides do not undergo nucleophilic substitution with anion formed by phthalimide.