Explanation:

Proteins are large biomolecules made up of amino acids. They play a crucial role in various biological processes and perform a wide range of functions in living organisms. However, proteins do not have the ability to generate their own replication, making option B incorrect.

Formation of polypeptide chains:
Proteins are formed by the linking of amino acids through peptide bonds. Amino acids are joined together in a specific sequence to form a polypeptide chain, which is the primary structure of a protein. This is a fundamental criterion that proteins fulfill.

Formation of alpha helix and beta sheets:
Proteins can adopt different secondary structures, including alpha helix and beta sheets. These secondary structures are stabilized by hydrogen bonding between the amino acid residues in the polypeptide chain. Alpha helix is a coiled structure, while beta sheets are formed by interactions between different segments of the polypeptide chain. This criterion is fulfilled by proteins.

Non covalent bonds are present between amino acids:
In addition to peptide bonds, proteins also contain various non-covalent bonds such as hydrogen bonds, electrostatic interactions, and hydrophobic interactions. These non-covalent bonds contribute to the stability and folding of the protein structure. This criterion is also fulfilled by proteins.

Generation of its replica:
Proteins cannot generate their own replication. Replication is a process specific to nucleic acids, such as DNA and RNA. Nucleic acids have the ability to replicate themselves by complementary base pairing and enzymatic processes. Proteins, on the other hand, are synthesized based on the information encoded in the nucleic acids. They do not possess the ability to replicate themselves.

In conclusion, while proteins fulfill the criteria of forming polypeptide chains, adopting secondary structures, and having non-covalent bonds between amino acids, they do not have the ability to generate their own replication, making option B the correct answer.