Cylindrical stone seals were primarily used in the Mesopotamian civilization, which is why the correct answer is option 'D'.

Mesopotamia was an ancient region located in the eastern Mediterranean, in what is now modern-day Iraq and Kuwait. It was one of the earliest civilizations in the world, and it is often referred to as the cradle of civilization. The Mesopotamian civilization emerged around 4000 BCE and lasted for several millennia.

The Mesopotamians used cylindrical stone seals as a form of identification and authentication. These seals were typically made of stone, such as limestone or steatite, and were cylindrical in shape with a flat base. They were often engraved with intricate designs or inscriptions.

The primary purpose of these seals was to mark ownership and protect property. They were commonly used to seal containers, such as jars or baskets, to ensure the contents remained secure. The seals were rolled onto clay or wax, leaving behind an impression that acted as a seal. This seal served as evidence of ownership or authorization.

The cylindrical stone seals often had a unique design or inscription that identified the owner. These designs could depict various motifs, such as animals, humans, or symbols representing gods or important concepts. The inscriptions could include the owner's name or other identifying information.

The use of cylindrical stone seals was not limited to just the Mesopotamian civilization. They were also used in other ancient civilizations, such as the Harappan civilization in the Indus Valley and the Egyptian civilization along the Nile River. However, the Mesopotamians were particularly known for their extensive use of these seals.

In conclusion, the cylindrical stone seals were primarily used in the Mesopotamian civilization. They served as a form of identification and authentication, used for marking ownership and protecting property. While they were also used in other civilizations, the Mesopotamians were renowned for their widespread use of these seals.