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Which of the following is incorrect with reference to the Xenotransplantation?
- a)It involves the infusion of organ into a human recipient from a nonhuman animal source.
- b)It targets only monkeys as source animals, with the goal of transplanting monkey’s solid organs such as kidneys and hearts.
- c)It is associated with immunological problems and xenogeneic infections.
- d)It has largely resulted in failure in the past due to high rejection rates in recipients.
Correct answer is option 'B'. Can you explain this answer?
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Which of the following is incorrect with reference to the Xenotranspl...
Option b is the correct answer.
- In January 2022, in a medical first, doctors transplanted a pig heart into a patient to save his life in the US.
- The patient was deemed ineligible for a conventional heart transplant or an artificial heart by leading transplant centres after a review of his medical records.
- Statement a is correct: Xenotransplantation is any procedure that involves the transplantation, implantation or infusion into a human recipient of either (a) live cells, tissues, or organs from a nonhuman animal source, or (b) human body fluids, cells, tissues or organs that have had ex vivo contact with live nonhuman animal cells, tissues or organs.
- One of the biggest obstacles to transplantation is organ rejection. In the above case, scientists have addressed the problem by genetically altering pigs’ organs. The donor pig underwent 10 genetic modifications, by which the genes responsible for the rapid rejection of foreign organs by the human body were inactivated or knocked out.
- Statement b is incorrect: Xenotransplantation targets pigs as source animals with the goal of transplanting pig solid organs, such as kidneys, hearts, and livers, into humans. In some cases, external (ex vivo) pig liver has been used for temporary perfusion for bridging acute liver failure. Among other goals are the use of encapsulated porcine islet cells for diabetes therapy and the use of fetal porcine neural stem cells for Parkinson cell therapy. The transplantation of inert animal material such as pig heart valves does not fall under this definition because they are no longer living tissues and are thus handled like inactive metal implants.
- Statement c is correct: Xenotransplantation is the transplantation of living tissue or organs from one species to another. It has long been hoped to be a solution for the supply issues facing liver transplantation. At the same time, xenotransplantation is associated with a number of concerns, including immunological problems and xenogeneic infections, as well as ethical, legal, and social concerns. Regardless of these issues, it is not an area that has had great success.
- Statement d is correct: Xenotransplantation involves the use of nonhuman animal sources for organs for transplantation into human beings and has been viewed as having the potential to address organ shortage. Attempts at xenotransplantation are not new but have largely resulted in failure in the past due to high rejection rates in recipients. The development of genetic engineering techniques led to renewed interest in the area because it was considered that such techniques could be used on nonhuman animals, such as pigs, in order to reduce, if not eliminate, problems of organ rejection or transmission of disease in the transplantation process.
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Which of the following is incorrect with reference to the Xenotransplantation?a)It involves the infusion of organ into a human recipient from a nonhuman animal source.b)It targets only monkeys as source animals, with the goal of transplanting monkey’s solid organs such as kidneys and hearts.c)It is associated with immunological problems and xenogeneic infections.d)It has largely resulted in failure in the past due to high rejection rates in recipients.Correct answer is option 'B'. Can you explain this answer?
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Which of the following is incorrect with reference to the Xenotransplantation?a)It involves the infusion of organ into a human recipient from a nonhuman animal source.b)It targets only monkeys as source animals, with the goal of transplanting monkey’s solid organs such as kidneys and hearts.c)It is associated with immunological problems and xenogeneic infections.d)It has largely resulted in failure in the past due to high rejection rates in recipients.Correct answer is option 'B'. Can you explain this answer? for UPSC 2025 is part of UPSC preparation. The Question and answers have been prepared according to the UPSC exam syllabus. Information about Which of the following is incorrect with reference to the Xenotransplantation?a)It involves the infusion of organ into a human recipient from a nonhuman animal source.b)It targets only monkeys as source animals, with the goal of transplanting monkey’s solid organs such as kidneys and hearts.c)It is associated with immunological problems and xenogeneic infections.d)It has largely resulted in failure in the past due to high rejection rates in recipients.Correct answer is option 'B'. Can you explain this answer? covers all topics & solutions for UPSC 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Which of the following is incorrect with reference to the Xenotransplantation?a)It involves the infusion of organ into a human recipient from a nonhuman animal source.b)It targets only monkeys as source animals, with the goal of transplanting monkey’s solid organs such as kidneys and hearts.c)It is associated with immunological problems and xenogeneic infections.d)It has largely resulted in failure in the past due to high rejection rates in recipients.Correct answer is option 'B'. Can you explain this answer?.
Which of the following is incorrect with reference to the Xenotransplantation?a)It involves the infusion of organ into a human recipient from a nonhuman animal source.b)It targets only monkeys as source animals, with the goal of transplanting monkey’s solid organs such as kidneys and hearts.c)It is associated with immunological problems and xenogeneic infections.d)It has largely resulted in failure in the past due to high rejection rates in recipients.Correct answer is option 'B'. Can you explain this answer? for UPSC 2025 is part of UPSC preparation. The Question and answers have been prepared according to the UPSC exam syllabus. Information about Which of the following is incorrect with reference to the Xenotransplantation?a)It involves the infusion of organ into a human recipient from a nonhuman animal source.b)It targets only monkeys as source animals, with the goal of transplanting monkey’s solid organs such as kidneys and hearts.c)It is associated with immunological problems and xenogeneic infections.d)It has largely resulted in failure in the past due to high rejection rates in recipients.Correct answer is option 'B'. Can you explain this answer? covers all topics & solutions for UPSC 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Which of the following is incorrect with reference to the Xenotransplantation?a)It involves the infusion of organ into a human recipient from a nonhuman animal source.b)It targets only monkeys as source animals, with the goal of transplanting monkey’s solid organs such as kidneys and hearts.c)It is associated with immunological problems and xenogeneic infections.d)It has largely resulted in failure in the past due to high rejection rates in recipients.Correct answer is option 'B'. Can you explain this answer?.
Solutions for Which of the following is incorrect with reference to the Xenotransplantation?a)It involves the infusion of organ into a human recipient from a nonhuman animal source.b)It targets only monkeys as source animals, with the goal of transplanting monkey’s solid organs such as kidneys and hearts.c)It is associated with immunological problems and xenogeneic infections.d)It has largely resulted in failure in the past due to high rejection rates in recipients.Correct answer is option 'B'. Can you explain this answer? in English & in Hindi are available as part of our courses for UPSC.
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