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The induced fit model of enzyme binding states that which of the following molecules alters the enzyme active site to more closely match the shape of the substrate?
- a)The substrate
- b)A cofactor
- c)A coenzyme
- d)An allosteric effector
Correct answer is option 'A'. Can you explain this answer?
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The induced fit model of enzyme binding states that which of the follo...
The induced fit model of enzyme binding describes the dynamic interaction between an enzyme and its substrate. According to this model, the active site of the enzyme undergoes a conformational change upon binding to the substrate. The initial active site may not perfectly match the shape of the substrate, but as the substrate binds, it induces a conformational change in the enzyme, leading to a more precise fit between the active site and the substrate.
The binding of the substrate induces changes in the enzyme's structure, such as alterations in the orientation of amino acid side chains, which allows for optimal interaction and formation of the enzyme-substrate complex. This conformational change enhances the catalytic activity of the enzyme and promotes the conversion of the substrate to product.
Cofactors and coenzymes (options B and C) are additional molecules that can assist enzyme activity by providing necessary chemical groups or aiding in electron transfer, but they do not directly alter the enzyme's active site to match the substrate. Allosteric effectors (option D) can modulate enzyme activity by binding to regulatory sites distinct from the active site, but they do not directly induce a conformational change in the active site to match the substrate.
Therefore, the substrate itself is the molecule that alters the enzyme active site to more closely match its shape in the induced fit model of enzyme binding.
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The induced fit model of enzyme binding states that which of the following molecules alters the enzyme active site to more closely match the shape of the substrate?a)The substrateb)A cofactorc)A coenzymed)An allosteric effectorCorrect answer is option 'A'. Can you explain this answer?
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