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Consider the following statements regarding Hemochromatosis.
- Hemochromatosis is a rare disorder characterized by iron overload.
- It can affect vital organs such as the liver, heart, and pancreas.
- Hemochromatosis is not a hereditary disorder.
How many of the above statements is/are correct?
- a)Only one
- b)Only two
- c)All three
- d)None
Correct answer is option 'B'. Can you explain this answer?
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Most Upvoted Answer
Consider the following statements regarding Hemochromatosis. Hemochrom...
Statement 1: Hemochromatosis is a rare disorder characterized by iron overload.
Hemochromatosis is indeed a disorder characterized by excessive absorption and accumulation of iron in the body. This excess iron is deposited in various organs and tissues, leading to their dysfunction over time. The disorder is commonly referred to as iron overload disease and is characterized by increased levels of iron in the blood.
Statement 2: It can affect vital organs such as the liver, heart, and pancreas.
This statement is correct. Hemochromatosis can affect vital organs such as the liver, heart, pancreas, and other organs. The excess iron deposition can lead to organ damage and impair their normal functions. The liver is particularly susceptible to iron overload, resulting in conditions such as cirrhosis and hepatocellular carcinoma. Iron accumulation in the heart can cause cardiomyopathy and arrhythmias, while the pancreas can be affected by diabetes mellitus.
Statement 3: Hemochromatosis is not a hereditary disorder.
This statement is incorrect. Hemochromatosis is primarily a hereditary disorder, meaning it is caused by genetic mutations that affect iron metabolism. The most common form of hemochromatosis is known as hereditary hemochromatosis (HH) and is inherited in an autosomal recessive manner. This means that both copies of the gene responsible for regulating iron absorption, called HFE gene, must be mutated for the disorder to manifest. Individuals who inherit two mutated copies of the HFE gene are at an increased risk of developing iron overload and hemochromatosis.
Therefore, out of the three statements, only statement 2 is correct, while statements 1 and 3 are incorrect. Hemochromatosis is a hereditary disorder characterized by iron overload that can affect vital organs such as the liver, heart, and pancreas.
Hemochromatosis is indeed a disorder characterized by excessive absorption and accumulation of iron in the body. This excess iron is deposited in various organs and tissues, leading to their dysfunction over time. The disorder is commonly referred to as iron overload disease and is characterized by increased levels of iron in the blood.
Statement 2: It can affect vital organs such as the liver, heart, and pancreas.
This statement is correct. Hemochromatosis can affect vital organs such as the liver, heart, pancreas, and other organs. The excess iron deposition can lead to organ damage and impair their normal functions. The liver is particularly susceptible to iron overload, resulting in conditions such as cirrhosis and hepatocellular carcinoma. Iron accumulation in the heart can cause cardiomyopathy and arrhythmias, while the pancreas can be affected by diabetes mellitus.
Statement 3: Hemochromatosis is not a hereditary disorder.
This statement is incorrect. Hemochromatosis is primarily a hereditary disorder, meaning it is caused by genetic mutations that affect iron metabolism. The most common form of hemochromatosis is known as hereditary hemochromatosis (HH) and is inherited in an autosomal recessive manner. This means that both copies of the gene responsible for regulating iron absorption, called HFE gene, must be mutated for the disorder to manifest. Individuals who inherit two mutated copies of the HFE gene are at an increased risk of developing iron overload and hemochromatosis.
Therefore, out of the three statements, only statement 2 is correct, while statements 1 and 3 are incorrect. Hemochromatosis is a hereditary disorder characterized by iron overload that can affect vital organs such as the liver, heart, and pancreas.
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Community Answer
Consider the following statements regarding Hemochromatosis. Hemochrom...
Statement 3 is incorrect.
Hemochromatosis is a rare genetic disorder characterized by iron overload, which can lead to severe dysfunction in various organs.
There are two main types of hemochromatosis: hereditary hemochromatosis and secondary hemochromatosis.
Hemochromatosis is a rare genetic disorder characterized by iron overload, which can lead to severe dysfunction in various organs.
There are two main types of hemochromatosis: hereditary hemochromatosis and secondary hemochromatosis.
- Hereditary Hemochromatosis: This genetic disorder results from a mutation in the HFE gene, causing individuals to absorb excessive iron from their diet.
- Unlike the body’s natural ability to regulate iron intake, people with hereditary hemochromatosis accumulate iron gradually in their system, which can lead to health problems over time.
- The excess iron can affect vital organs such as the liver, heart, and pancreas, potentially causing cirrhosis, heart failure, diabetes, and arthritis.
- Secondary Hemochromatosis: This type is typically caused by external factors like frequent blood transfusions, excessive iron supplementation, or certain medical conditions. Iron accumulation in secondary hemochromatosis can be more rapid and lead to organ dysfunction.
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Consider the following statements regarding Hemochromatosis. Hemochromatosis is a rare disorder characterized by iron overload. It can affect vital organs such as the liver, heart, and pancreas. Hemochromatosis is not a hereditary disorder.How many of the above statements is/are correct?a)Only oneb)Only twoc)All threed)NoneCorrect answer is option 'B'. Can you explain this answer?
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