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Consider the following statements with reference to the Recombinant Proteins:
1. It is a manipulated form of native protein, which is generated in various ways to increase production of proteins.
2. It is used to produce protein-based polymers for drug delivery.
Which of the statements given above is/are correct?
  • a)
    1 only
  • b)
    2 only
  • c)
    Both 1 and 2
  • d)
    Neither 1 nor 2
Correct answer is option 'C'. Can you explain this answer?
Verified Answer
Consider the following statements with reference to the Recombinant Pr...
Researchers at the Department of Biochemistry, Indian Institute of Science, have developed a novel method for the production of recombinant proteins.
  • These are proteins encoded by recombinant DNA that has been cloned in an expression vector that supports expression of the gene and translation of messenger RNA.
  • Modification of the gene by recombinant DNA technology can lead to expression of a mutant protein.
  • It is a manipulated form of native protein, which is generated in various ways in order to increase production of proteins, modify gene sequences, and manufacture useful commercial products.
  • It is created by fusing sequences that may not be normally present in an organism.
  • Recombinant proteins, such as vaccine antigens, insulin and monoclonal antibodies, are mass-produced by growing modified bacterial, viral or mammalian cells in large bioreactors. The most widely used organism is the yeast Pichia pastoris (now called Komagataella phaffii).
  • Application of Recombinant Proteins
  • It used in biomedical research to understand health and disease.
  • It is used in biotherapeutics.
  • It is used to produce protein-based polymers for drug delivery, antibodies and enzymes for disease treatment, protein scaffolds for tissue engineering etc.
What is protein?
  • It is the workhorse in biological systems facilitating most of biological processes in a cell, including gene expression, cell growth, proliferation, nutrient uptake, intercellular communication and apoptosis.
  • The blue print for protein synthesis is stored in DNA, which serves as a template for highly regulated transcriptional processes to produce messenger RNA (mRNA). 
Hence both statements are correct.
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Consider the following statements with reference to the Recombinant Proteins:1. It is a manipulated form of native protein, which is generated in various ways to increase production of proteins.2. It isused to produce protein-based polymers for drug delivery.Which of the statements given above is/are correct?a)1 onlyb)2 onlyc)Both 1 and 2d)Neither 1 nor 2Correct answer is option 'C'. Can you explain this answer?
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