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How do GLP-1 receptor agonists function in the body?
- a)They increase glucagon levels to raise blood sugar
- b)They mimic the action of GLP-1 to enhance insulin secretion
- c)They inhibit appetite by blocking all hormonal signals
- d)They promote lipid metabolism by reducing insulin sensitivity
Correct answer is option 'B'. Can you explain this answer?
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How do GLP-1 receptor agonists function in the body?a) They increase g...
GLP-1 receptor agonists function by mimicking the natural hormone GLP-1, which is crucial for regulating appetite and blood sugar levels. When these medications bind to GLP-1 receptors, they stimulate insulin secretion and reduce glucagon release, leading to better blood sugar control. This mechanism not only aids in diabetes management but also supports weight loss, making these drugs a significant advancement in treating obesity and related metabolic disorders. An interesting fact is that these medications are typically administered via injection, highlighting their potency and targeted delivery in managing metabolic health.
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How do GLP-1 receptor agonists function in the body?a) They increase g...
Understanding GLP-1 Receptor Agonists
GLP-1 (glucagon-like peptide-1) receptor agonists are medications primarily used to manage type 2 diabetes and, more recently, obesity. Their mechanism of action mimics the natural hormone GLP-1, which plays a crucial role in glucose metabolism.
Mechanism of Action
- Enhances Insulin Secretion:
- GLP-1 receptor agonists stimulate the pancreatic beta cells to release insulin in response to elevated blood glucose levels. This is known as glucose-dependent insulin secretion, meaning that insulin is only released when blood sugar levels are high.
- Suppresses Glucagon Release:
- These agonists also work to lower glucagon levels, a hormone that raises blood sugar levels. By reducing glucagon secretion, they help to prevent the liver from producing excessive glucose, thereby lowering overall blood sugar levels.
Additional Benefits
- Slows Gastric Emptying:
- They slow the emptying of the stomach, leading to prolonged feelings of fullness and reduced appetite, which is beneficial for weight management.
- Promotes Satiety:
- The action of GLP-1 in the brain can enhance satiety signals, helping individuals consume fewer calories.
- Cardiovascular Benefits:
- Some GLP-1 receptor agonists have shown positive effects on cardiovascular health, reducing the risk of heart disease.
Conclusion
Option 'B' is correct as GLP-1 receptor agonists effectively mimic the action of GLP-1, enhancing insulin secretion and lowering blood sugar levels, making them valuable in diabetes and weight management.
GLP-1 (glucagon-like peptide-1) receptor agonists are medications primarily used to manage type 2 diabetes and, more recently, obesity. Their mechanism of action mimics the natural hormone GLP-1, which plays a crucial role in glucose metabolism.
Mechanism of Action
- Enhances Insulin Secretion:
- GLP-1 receptor agonists stimulate the pancreatic beta cells to release insulin in response to elevated blood glucose levels. This is known as glucose-dependent insulin secretion, meaning that insulin is only released when blood sugar levels are high.
- Suppresses Glucagon Release:
- These agonists also work to lower glucagon levels, a hormone that raises blood sugar levels. By reducing glucagon secretion, they help to prevent the liver from producing excessive glucose, thereby lowering overall blood sugar levels.
Additional Benefits
- Slows Gastric Emptying:
- They slow the emptying of the stomach, leading to prolonged feelings of fullness and reduced appetite, which is beneficial for weight management.
- Promotes Satiety:
- The action of GLP-1 in the brain can enhance satiety signals, helping individuals consume fewer calories.
- Cardiovascular Benefits:
- Some GLP-1 receptor agonists have shown positive effects on cardiovascular health, reducing the risk of heart disease.
Conclusion
Option 'B' is correct as GLP-1 receptor agonists effectively mimic the action of GLP-1, enhancing insulin secretion and lowering blood sugar levels, making them valuable in diabetes and weight management.
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How do GLP-1 receptor agonists function in the body?a) They increase glucagon levels to raise blood sugarb) They mimic the action of GLP-1 to enhance insulin secretionc) They inhibit appetite by blocking all hormonal signalsd) They promote lipid metabolism by reducing insulin sensitivityCorrect answer is option 'B'. Can you explain this answer?
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How do GLP-1 receptor agonists function in the body?a) They increase glucagon levels to raise blood sugarb) They mimic the action of GLP-1 to enhance insulin secretionc) They inhibit appetite by blocking all hormonal signalsd) They promote lipid metabolism by reducing insulin sensitivityCorrect answer is option 'B'. Can you explain this answer? for Bank Exams 2024 is part of Bank Exams preparation. The Question and answers have been prepared according to the Bank Exams exam syllabus. Information about How do GLP-1 receptor agonists function in the body?a) They increase glucagon levels to raise blood sugarb) They mimic the action of GLP-1 to enhance insulin secretionc) They inhibit appetite by blocking all hormonal signalsd) They promote lipid metabolism by reducing insulin sensitivityCorrect answer is option 'B'. Can you explain this answer? covers all topics & solutions for Bank Exams 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for How do GLP-1 receptor agonists function in the body?a) They increase glucagon levels to raise blood sugarb) They mimic the action of GLP-1 to enhance insulin secretionc) They inhibit appetite by blocking all hormonal signalsd) They promote lipid metabolism by reducing insulin sensitivityCorrect answer is option 'B'. Can you explain this answer?.
How do GLP-1 receptor agonists function in the body?a) They increase glucagon levels to raise blood sugarb) They mimic the action of GLP-1 to enhance insulin secretionc) They inhibit appetite by blocking all hormonal signalsd) They promote lipid metabolism by reducing insulin sensitivityCorrect answer is option 'B'. Can you explain this answer? for Bank Exams 2024 is part of Bank Exams preparation. The Question and answers have been prepared according to the Bank Exams exam syllabus. Information about How do GLP-1 receptor agonists function in the body?a) They increase glucagon levels to raise blood sugarb) They mimic the action of GLP-1 to enhance insulin secretionc) They inhibit appetite by blocking all hormonal signalsd) They promote lipid metabolism by reducing insulin sensitivityCorrect answer is option 'B'. Can you explain this answer? covers all topics & solutions for Bank Exams 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for How do GLP-1 receptor agonists function in the body?a) They increase glucagon levels to raise blood sugarb) They mimic the action of GLP-1 to enhance insulin secretionc) They inhibit appetite by blocking all hormonal signalsd) They promote lipid metabolism by reducing insulin sensitivityCorrect answer is option 'B'. Can you explain this answer?.
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How do GLP-1 receptor agonists function in the body?a) They increase glucagon levels to raise blood sugarb) They mimic the action of GLP-1 to enhance insulin secretionc) They inhibit appetite by blocking all hormonal signalsd) They promote lipid metabolism by reducing insulin sensitivityCorrect answer is option 'B'. Can you explain this answer?, a detailed solution for How do GLP-1 receptor agonists function in the body?a) They increase glucagon levels to raise blood sugarb) They mimic the action of GLP-1 to enhance insulin secretionc) They inhibit appetite by blocking all hormonal signalsd) They promote lipid metabolism by reducing insulin sensitivityCorrect answer is option 'B'. Can you explain this answer? has been provided alongside types of How do GLP-1 receptor agonists function in the body?a) They increase glucagon levels to raise blood sugarb) They mimic the action of GLP-1 to enhance insulin secretionc) They inhibit appetite by blocking all hormonal signalsd) They promote lipid metabolism by reducing insulin sensitivityCorrect answer is option 'B'. Can you explain this answer? theory, EduRev gives you an
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