Patients suffering from Wilson’s disease have:a)Low level of Cu&...
Wilson disease is a genetic disease that prevents the body from removing extra copper. ... In Wilson disease, the liver does not filter copper correctly and copper builds up in the liver, brain, eyes, and other organs. Over time, high copper levels can cause life-threatening organ damage. In Wilson's disease, a particular gene on chromosome 13 does not work. The gene is called ATP7B. This gene normally controls the way the liver cells get rid of excess copper. Normally, the liver cells pass out excess copper into the bile. If this process does not work then the copper builds up in liver cells. When the copper storage capacity of the liver cells is exhausted, the copper spills into the bloodstream and deposits in other parts of the body, mainly the brain.
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Patients suffering from Wilson’s disease have:a)Low level of Cu&...
Wilson's disease and Copper Storage Protein
Wilson's disease is a genetic disorder that causes an accumulation of copper in the body. This excess copper can be toxic, leading to damage to the liver, brain, and other organs. Copper storage protein, ceruloplasmin, plays a crucial role in regulating copper levels in the body.
Low Level of Copper Storage Protein
In Wilson's disease, there is a low level of copper storage protein, ceruloplasmin. This is due to a genetic mutation that impairs the liver's ability to produce ceruloplasmin. As a result, copper accumulates in the body, leading to a range of symptoms and complications.
High Level of Copper Storage Protein
Although Wilson's disease is characterized by a low level of ceruloplasmin, the body may produce more of this protein in response to the excess copper. This overproduction of ceruloplasmin is an attempt to bind and eliminate the excess copper from the body.
Conclusion
In summary, patients suffering from Wilson's disease have a low level of copper storage protein, ceruloplasmin. However, the body may produce more ceruloplasmin in response to the excess copper, leading to a high level of this protein in some cases.
Patients suffering from Wilson’s disease have:a)Low level of Cu&...
C is correct answer but net gives answer d
when ceruloplasmin protein is more then cu to ek bhi ni bacheha