Primary amides get converted into primary amines by:a)Additionb)Oxidat...
Acid chlorides react with ammonia, a primary amine, or a secondary amine to give primary, secondary, and tertiary amides, respectively. Tertiary amines do not react with acid chlorides to give amides. An amide is a weak base.Oxidation is any chemical reaction that involves the moving of electrons. Specifically, it means the substance that gives away electrons is oxidized.
When iron reacts with oxygen it forms a chemical called rust because it has been oxidized (The iron has lost some electrons.) and the oxygen has been reduced (The oxygen has gained some electrons.).
Oxidation is the opposite of reduction. A reduction-reaction always comes together with an oxidation-reaction. Oxidation and reduction together are called redox (reduction and oxidation). Oxygen does not have to be present in a reaction, for it to be a redox-reaction.
Oxidation is the loss of electrons.
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Primary amides get converted into primary amines by:a)Additionb)Oxidat...
Explanation:
Primary amides can be converted into primary amines through a process called oxidation. Oxidation involves the addition of oxygen or the removal of hydrogen from a compound. In the case of primary amides, the oxidation process involves the removal of the carbonyl group (C=O) and the addition of a hydrogen atom. This results in the conversion of the amide functional group (NH2) into an amine functional group (NH2).
Process of Oxidation:
The oxidation of primary amides to primary amines can be achieved using various oxidizing agents such as hydrogen peroxide (H2O2) or sodium hypochlorite (NaClO). These oxidizing agents provide the necessary oxygen atoms for the oxidation process.
Reaction:
The oxidation of a primary amide can be represented by the following reaction:
RCONH2 + [O] → RCH2NH2 + CO2
In this reaction, R represents an alkyl or aryl group. The primary amide (RCONH2) reacts with the oxidizing agent ([O]) to produce a primary amine (RCH2NH2) and carbon dioxide (CO2) as a byproduct.
Example:
For example, the oxidation of acetamide (CH3CONH2) can be achieved using hydrogen peroxide as the oxidizing agent. The reaction can be represented as follows:
CH3CONH2 + H2O2 → CH3CH2NH2 + CO2
In this reaction, acetamide is oxidized to produce ethylamine and carbon dioxide.
Application:
The oxidation of primary amides to primary amines is an important reaction in organic synthesis. It allows for the conversion of amides, which are commonly found in many natural and synthetic compounds, into primary amines, which have a wide range of applications in pharmaceuticals, agrochemicals, and materials science.
Conclusion:
In conclusion, primary amides can be converted into primary amines through the process of oxidation. This reaction involves the removal of the carbonyl group and the addition of a hydrogen atom, resulting in the conversion of the amide functional group into an amine functional group. The oxidation of primary amides to primary amines is an important reaction in organic synthesis and has various applications in different fields.